Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
PHASE2
40 participants
INTERVENTIONAL
2024-01-01
2026-01-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Clinical Evaluation of the Efficacy OF Botulinum Toxin A for Improving Facial Scars
NCT04756882
Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"
NCT06437912
Botulinum Toxin Injection in Reducing Scar Following Cheilorrhaphy.
NCT07137234
Fields Of Effects Of Two Commercial Preparations Of Botulinum Toxin Type A At Equal Labeled Unit Doses
NCT01732809
Onabotulinum Toxin A in Direct Brow Lift
NCT04383912
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
There are several procedures to address this condition, but none of them is undoubtedly superior to the others. The direct eyebrow lift technique is known for providing good eyebrow suspension, predictable results and relatively low complexity surgery, which can be performed with local anesthesia.
However, the biggest concern for surgeons and patients is the final appearance of the scar, which will be in a visible area of the face. Botulinum toxin A has been used in recent studies precisely to improve the appearance of scars. Previous studies mainly evaluated traumatic lacerations and post-tumor excision reconstructions, obtaining positive results, with an improvement in the appearance of the wounds in patients who used the medication. It is a safe drug, used for several years for other purposes and without serious adverse effects according to these studies.
The objective of this study is to compare the use of botulinum toxin A versus 0.9% saline solution in the healing of direct eyebrow lift surgery.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Right side treatment
Patients receive botulinum toxin A in right side eyebrow scar and saline in left side scar.
Botulinum toxin type A
Botulinum toxin application between 3-14 days after direct eyebrow lift surgery.
Left side treatment
Patients receive botulinum toxin A in left side eyebrow scar and saline in right side scar.
Botulinum toxin type A
Botulinum toxin application between 3-14 days after direct eyebrow lift surgery.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Botulinum toxin type A
Botulinum toxin application between 3-14 days after direct eyebrow lift surgery.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Allergy to botulinum toxin A
* Patients under 18 years old
* Women who are breastfeeding
* Patients with muscular/neuromuscular diseases such as myasthenia gravis and amyotrophic lateral sclerosis
* Patients who underwent botulinum toxin A injection in the last 6 months prior to surgery
* Patients with a history of radiotherapy, chemotherapy or hematological disorders
* Refusal to participate in the study
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Campinas, Brazil
OTHER
Faculdade de Medicina do ABC
OTHER
University of Sao Paulo
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Suzana Matayoshi
Professor
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of São Paulo (Clinical Hospital)
São Paulo, , Brazil
Ophthalmology Dept. University of Sao Paulo General Hospital
São Paulo, , Brazil
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
73675523.7.0000.0068
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.