Mayo Clinic Tapestry 2.0: Applying Multi-Omics for Scientific Discovery

NCT ID: NCT06456320

Last Updated: 2025-10-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-05

Study Completion Date

2027-12-31

Brief Summary

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The purpose of this study is to use multi-omics testing on samples collected from Mayo Clinic patients to build and expand on what has been learned about genomic data.

Detailed Description

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Conditions

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Genetic Predisposition Exposure, Environmental

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Suspected Genetic Predisposition or Multi-Omics Contribution

Patients with a diagnosis or phenotype with the potential for association with a genetic predisposition or Multi-Omics Contribution.

No interventions assigned to this group

Healthy Control

Patients with no diagnosis associated with a genetic predisposition or Multi-Omics Contribution.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Registered Mayo Clinic patient
* Able to provide informed written consent
* Able to receive mail and packages within a United States (US) state
* Able to collect and ship samples within a US state

Exclusion Criteria

* Active hematological cancer or history of a hematological cancer
* Allogeneic Bone Marrow Transplant (e.g., samples from autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
* Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study (e.g., reduced ability to comprehend, i.e., dementia, intellectual disability, etc.)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Konstantinos N. Lazaridis, M.D.

Executive Director, Center for Individualized Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Konstantinos N. Lazaridis, M.D.

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic in Arizona

Scottsdale, Arizona, United States

Site Status

Mayo Clinic in Florida

Jacksonville, Florida, United States

Site Status

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Site Status

Countries

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United States

Other Identifiers

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23-004120

Identifier Type: -

Identifier Source: org_study_id

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