Vascular Access for Minimally-invasive Leadless Pacemaker Implantation Through the Right Jugular routE

NCT ID: NCT06455566

Last Updated: 2025-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-05-01

Study Completion Date

2027-05-01

Brief Summary

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Leadless pacemakers (LP) are associated with a lower risk of revision compared with transvenous pacemakers. However, LPs implantation is associated with a 0.6% risk of complication at the femoral vein puncture site (e.g. arteriovenous fistula, haemorrhage, pseudoaneurysm, etc.). As a consequence, the need for prolonged in-hospital monitoring after LP implantation though the right femoral (RF)vein is a barrier to same-day discharge. Recently, right internal jugular (RIJ) vein access has emerged an alternative to right RF vein access for LP implantation (with a regulatory approval for MEDTRONIC Micra LP).

The aims of this registry are the following :

* evaluate the feasibility of RIJ access for LP implantation;
* confirm the acute and chronic safety of RIJ access for LP implantation;
* compare RIJ to RF (historical cohort) vein access regarding procedural characteristics and outcomes;
* evaluate the feasibility of same-day discharge avec LP implantation through the RIJ vein.

Detailed Description

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Conditions

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Leadless Pacemaker Same-day Discharge

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Leadless pacemaker implantation through right internal jugular vein

Leadless pacemaker implantation through right internal jugular vein

Intervention Type DEVICE

Leadless pacemaker implantation through right internal jugular vein

Interventions

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Leadless pacemaker implantation through right internal jugular vein

Leadless pacemaker implantation through right internal jugular vein

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Indication of pacemaker implantation
* Eligible to leadless pacemaker

Exclusion Criteria

* Contraindication to right internal jugular vein access
* Age \< 18 year-old
* Patient already included in a clinical study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Caen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Angers University Hospital

Angers, , France

Site Status

Caen University Hospital

Caen, , France

Site Status

Grenoble University Hospital

Grenoble, , France

Site Status

Lille University Hospital

Lille, , France

Site Status

Lyon University Hospital

Lyon, , France

Site Status

Metz-Thionville Regional Hospital

Metz, , France

Site Status

Le Millénaire Private Hospital

Montpellier, , France

Site Status

Les Franciscaines Private Hospital

Nîmes, , France

Site Status

Rennes University Hospital

Rennes, , France

Site Status

La Réunion University Hospital

Saint Pierre de La Réunion, , France

Site Status

Strasbourg University Hospital

Strasbourg, , France

Site Status

Toulouse University Hospital

Toulouse, , France

Site Status

Tours University Hospital

Tours, , France

Site Status

Countries

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France

References

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El-Chami MF, Garweg C, Clementy N, Al-Samadi F, Iacopino S, Martinez-Sande JL, Roberts PR, Tondo C, Johansen JB, Vinolas-Prat X, Cha YM, Grubman E, Bordachar P, Stromberg K, Fagan DH, Piccini JP. Leadless pacemakers at 5-year follow-up: the Micra transcatheter pacing system post-approval registry. Eur Heart J. 2024 Apr 7;45(14):1241-1251. doi: 10.1093/eurheartj/ehae101.

Reference Type RESULT
PMID: 38426911 (View on PubMed)

Saleem-Talib S, van Driel VJ, Chaldoupi SM, Nikolic T, van Wessel H, Borleffs CJW, Ramanna H. Leadless pacing: Going for the jugular. Pacing Clin Electrophysiol. 2019 Apr;42(4):395-399. doi: 10.1111/pace.13607. Epub 2019 Feb 25.

Reference Type RESULT
PMID: 30653690 (View on PubMed)

Saleem-Talib S, van Driel VJ, Nikolic T, van Wessel H, Louman H, Borleffs CJW, van der Heijden J, Cox M, Ramanna H. The jugular approach for leadless pacing: A novel and safe alternative. Pacing Clin Electrophysiol. 2022 Oct;45(10):1248-1254. doi: 10.1111/pace.14587. Epub 2022 Sep 12.

Reference Type RESULT
PMID: 36031774 (View on PubMed)

Other Identifiers

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RYTHMO-2024-01

Identifier Type: -

Identifier Source: org_study_id

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