7.0T Magnetic Resonance Imaging Study of Parkinson's Disease

NCT ID: NCT06449404

Last Updated: 2024-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-01

Study Completion Date

2030-07-01

Brief Summary

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This clinical trial study is conducted to detect the imaging characteristics of the patients with Parkinson's diseases (PD) by 7-Tesla (7T) magnetic resonance imaging (MRI).

Detailed Description

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In this study,we explored the imaging characteristics of PD. First, with the advantage of 7T, we detect the slight changes of PD with short diseases history compared with the healthy. Second, we investigate the different imaging characteristics in subtypes of PD, finding the effective neuroimaging biomarkers to distinguish different subtypes of PD. Finally, we take long time follow-up to evaluate the correlation between the imaging changes and clinical score alteration in PD.

Conditions

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Parkinson's Diseases MRI

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

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7T-MRI scaning

7T-MRI scaning

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* the patients with PD who was diagnosed by the experienced neurologist specializing in movement disorders

Exclusion Criteria

* the patients with brain disorders such as cerebrovascular disease, brain tumors, epilepsy, other neurodegenerative disease;
* psychiatric disorders with impaired cognitive function;
* contraindications to MRI.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese PLA General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Xin Lou

Director and Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Chinese PLA General Hospital

Beijing, Beijing, China, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Haoxaun Lu

Role: CONTACT

18813137635

Facility Contacts

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Haoxuan Lu

Role: primary

18813137635

Other Identifiers

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Parkinson's disease-ChinaPLAGH

Identifier Type: -

Identifier Source: org_study_id

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