Assessing the Clinical Efficacy of Hyaluronic Acid Hydrogel in Papilla Augmentation: A Clinical Study.

NCT ID: NCT06447311

Last Updated: 2024-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-10

Study Completion Date

2024-06-30

Brief Summary

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The aim of this study is to evaluate the effect of hyaluronic acid gel in papilla augmentation.

Detailed Description

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Assessing the clinical efficacy of Hyaluronic acid hydrogel in papilla augmentation: A clinical study.

In Test group, Hyaluronic acid hydrogel will be injected using a syringe into the interdental papillary deficiency site.

In Control group, saline placebo gel will be injected into the interdental papillary deficiency site using a syringe.

Conditions

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Gingival Destruction

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Test group

In Test group, the prepared Hyaluronic acid gel will be injected using a syringe into the defect site.

Group Type EXPERIMENTAL

Hyaluronic acid gel

Intervention Type OTHER

Hyaluronic acid is involved in tissue repair and wound healing by stimulating cell proliferation, migration and interaction with several growth factors. Furthermore, HA has a crucial role in space-filling owing to its hygroscopic nature.

Control group

In Control group, saline placebo gel will be injected into the defect site using a syringe.

Group Type PLACEBO_COMPARATOR

Hyaluronic acid gel

Intervention Type OTHER

Hyaluronic acid is involved in tissue repair and wound healing by stimulating cell proliferation, migration and interaction with several growth factors. Furthermore, HA has a crucial role in space-filling owing to its hygroscopic nature.

Interventions

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Hyaluronic acid gel

Hyaluronic acid is involved in tissue repair and wound healing by stimulating cell proliferation, migration and interaction with several growth factors. Furthermore, HA has a crucial role in space-filling owing to its hygroscopic nature.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Non-smoking patients aged above 18 years.
2. Have at least one site with interdental papilla recession in the anterior region (central incisors, lateral incisors and canines) of the maxillary or mandibular jaws.
3. Class I or Class II papillary recession.
4. The distance from the contact point to alveolar bone crest ≥5mm.
5. No active periodontal diseases and good oral hygiene.

Exclusion Criteria

1. spacing or crowding between the teeth to be treated,
2. abnormal tooth shape,
3. systemic diseases such as diabetes mellitus, hypertension or
4. conditions that alter the outcome of periodontal therapy.
5. Pregnant and lactating women and
6. tobacco users
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Dr R Viswa Chandra

OTHER

Sponsor Role lead

Responsible Party

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Dr R Viswa Chandra

PROFFESSOR AND HEAD OF THE DEPARTMENT

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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SVS Institute of dental sciences

Mahbūbnagar, Telangana, India

Site Status RECRUITING

Countries

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India

Central Contacts

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Dr.viswa chandra, MDS

Role: CONTACT

8897819848

Facility Contacts

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VISWA CHANDRA, MDS;DNB;PhD

Role: primary

9908183071

Other Identifiers

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SVSInstituteDS4

Identifier Type: -

Identifier Source: org_study_id

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