Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)

NCT ID: NCT06445127

Last Updated: 2025-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

15 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-05-07

Study Completion Date

2025-04-08

Brief Summary

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This study is being done to find out if a non-invasive Magnetic Resonance Imaging (MRI) examination of the kidneys may be helpful in patients with systemic lupus erythematosus (SLE).

Detailed Description

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Conditions

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SLE (Systemic Lupus)

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Known Lupus Nephritis, with elevated UPCR result

Patients will have one scan at baseline, and one every 4 weeks thereafter for 3 visits. The final imaging session is after 6 months of routine therapy.

No interventions assigned to this group

No known lupus nephritis

Patients will have one MRI

No interventions assigned to this group

Known Lupus Nephritis, with normal Urine Protein Creatinine Ratio (UPCR) result

Patients will have one scan at baseline, and one every 4 weeks thereafter for 3 visits.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male and female adults over the age of 18 who have been diagnosed with SLE and are able to undergo a kidney MRI.

Exclusion Criteria

* Any patient that has undergone a renal transplant.
* Any patient that is receiving renal dialysis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Janssen Scientific Affairs, LLC

INDUSTRY

Sponsor Role collaborator

Johns Hopkins University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Homa Timlin, MD, MSc, MRCP, CCST

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins School of Medicine

Locations

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Johns Hopkins University School of Medicine

Baltimore, Maryland, United States

Site Status

Countries

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United States

Other Identifiers

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IRB00354110

Identifier Type: -

Identifier Source: org_study_id

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