Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI

NCT ID: NCT06435728

Last Updated: 2024-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

1297 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-01

Study Completion Date

2024-05-30

Brief Summary

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Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship between FFR and IMR and the prognosis of patients with acute myocardial infarction was analyzed

Detailed Description

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We retrospectively enrolled STEMI patients who underwent PCI in Peking University Third Hospital. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were obtained by analyzing the coronary angiography images. The prognosis of patients was obtained by searching inpatient and outpatient systems and telephone follow-up. The relationship between AccuFFR, AccuIMR and prognosis was statistically analyzed

Conditions

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Acute ST Segment Elevation Myocardial Infarction Prognosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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STEMI

Patients with STEMI who underwent primary PCI and were hospitalized at Peking University Third Hospital between January 2017 and March 2022

AccuIMR and AccuFFR

Intervention Type DIAGNOSTIC_TEST

AccuFFR and AccuIMR were obtained by reviewing coronary angiography at the time of primary PCI

Interventions

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AccuIMR and AccuFFR

AccuFFR and AccuIMR were obtained by reviewing coronary angiography at the time of primary PCI

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age of \>18 years;
* Onset-to-treatment time of ≤12 h, meeting the diagnostic criteria for STEMI;
* underwent primary PCI within 12 h of symptom onset and achieved successful PCI in the culprit vessel;
* Availability of complete clinical data

Exclusion Criteria

* severe tortuosity and overlap of the target vessel;
* poor-quality coronary angiography images;
* missing two coronary angiography images \>25° apart
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University Third Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ming Cui, Dorctor

Role: PRINCIPAL_INVESTIGATOR

Peking University Third Hospital

Locations

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Peking University Third Hospital

Beijing, , China

Site Status

Countries

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China

References

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Li J, Xie P, Hu Y, Zhou Y, Zhao W, Xu X, Zhu D, Mi L, Xiang J, Cui M. Predictive Value of Combining Angio-Based Index of Microcirculatory Resistance and Fractional Flow Reserve in Patients with STEMI. Can J Cardiol. 2025 Jul;41(7):1363-1371. doi: 10.1016/j.cjca.2025.02.003. Epub 2025 Feb 6.

Reference Type DERIVED
PMID: 39922306 (View on PubMed)

Other Identifiers

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D2023173

Identifier Type: -

Identifier Source: org_study_id

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