Cancer Prevention Among Individuals with Mental Ill-health: Patient Navigation for Primary Cancer Prevention

NCT ID: NCT06435117

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

1240 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-24

Study Completion Date

2025-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Prevention is essential for reducing cancer-related mortality. However, people with mental ill-health often face difficulties in accessing cancer prevention services. The EU-funded CO-CAPTAIN project aims to co-adapt and implement the Patient Navigation Model for primary cancer prevention in this underserved population. This evidence-based and patient-centred intervention aims to support patient empowerment through removal of systemic barriers, provide social support and promote timely access to primary prevention services.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Cancer and mental ill-health constitute leading public health problems in Europe. More than 84 million people in the European Union (EU) report living with an on-going mental ill-health condition. While issues concerning mental health are of great importance, they often overshadow physical problems that people with mental ill-health face. Such is cancer, which is more prevalent in people with mental ill-health and is also the second most common cause of death in this population. People with mental ill-health often have difficulties in accessing quality cancer prevention services, but are also additionally overlooked in research which makes them overall an underserved population. What data is available, shows that potential reasons for these higher cancer morbidity and mortality rates are linked to more engagement in risky health behaviour (especially higher prevalence of smoking as well as overweight and obesity) but also experiences of significant barriers when accessing the highly fragmented heath care systems.

Timely and evidence-based preventive strategies including optimizing health care pathways provide a solution to the high cancer morbidity and could improve overall health outcomes in this disadvantaged population. One such mixed-skill strategy is Patient Navigation. Therefore, the overall goal of the CO-CAPTAIN project is to co-adapt the Patient Navigation (PN) model focusing on primary cancer prevention and to see if this model can prove to be beneficial in supporting individuals with mental ill-health through care services to reduce cancer risk factors by increasing knowledge, health literacy and empowerment. The Patient Navigation Model is an innovative, evidence-based and patient-centred intervention, which supports patient empowerment through removal of systemic barriers, providing social support and promoting timely access to primary prevention services. Based on implementation science and utilizing the Consolidated Framework for Implementation (CFIR) as well as the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) frameworks, the CO-CAPTAIN project aims to reduce the gap in health inequalities for people with mental ill-health by reducing cancer burden and improving overall health, which will, in turn, reduce associated costs across health and social care systems in Europe. Moreover, the CO-CAPTAIN project aims to harness the transformative potential of the integrated care pathways in cancer as well as provide health and social care policy recommendations for the adoption and implementation of the Patient Navigation Model across Europe.

The adapted Patient Navigation Model will be implemented in four European countries (Austria, Greece, Poland, Spain) and its potential to enable and improve access and utilization of primary cancer prevention measures for people with mental ill-health will be evaluated. The study will employ a mixed-methods design allowing for both exploratory and confirmatory research.

The project has been funded by the HORIZON EUROPE Framework Program (Call: Research and Innovation actions supporting the implementation of the Mission on Cancer (HORIZON-MISS-2022-CANCER-01-01) - Improving and upscaling primary prevention of cancer through implementation research) and is coordinated by the Medical University of Vienna.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

People with mental ill-health

All people with mental ill-health aged 18 or older who visit one of the recruitment sites will be asked to participate. Further participants will be recruited through partner organizations (non-governmental organisations, patient groups and professional organisations) involved in care for individuals with mental ill-health, as well as personal contacts. Additionally, healthcare professionals involved in care of people with mental ill-health will be asked to participate in the qualitative part of the study.

Group Type OTHER

Patient Navigation

Intervention Type OTHER

CO-CAPTAIN focuses on co-designing and piloting and evaluating the implementation of patient navigation (PN) for primary cancer prevention in people with mental ill-health. Patient Navigators, trained professionals with experience working with people with mental ill-health, will assist people with mental ill-health in gaining access to and utilizing appropriate primary cancer prevention measures offered within the respective healthcare and social system (including smoking cessation and physical activity and nutritional interventions). For this purpose, Patient Navigators will offer regular appointment with participants, apply motivational interviewing and aid in accessing appropriate materials while aiming at empowering participants in taking an active role and making better and more informed decisions regarding their health.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Patient Navigation

CO-CAPTAIN focuses on co-designing and piloting and evaluating the implementation of patient navigation (PN) for primary cancer prevention in people with mental ill-health. Patient Navigators, trained professionals with experience working with people with mental ill-health, will assist people with mental ill-health in gaining access to and utilizing appropriate primary cancer prevention measures offered within the respective healthcare and social system (including smoking cessation and physical activity and nutritional interventions). For this purpose, Patient Navigators will offer regular appointment with participants, apply motivational interviewing and aid in accessing appropriate materials while aiming at empowering participants in taking an active role and making better and more informed decisions regarding their health.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 years of age or older
* Individuals who have been diagnosed with one or more mental disorders OR healthcare professionals involved in care of individuals with mental ill-health
* Sufficient knowledge of language

Exclusion Criteria

* Individuals unable to give consent due to diminished capacity
* Individuals who do not provide consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Medical University of Vienna

OTHER

Sponsor Role lead

Senior Europa Sociedad Limitada

UNKNOWN

Sponsor Role collaborator

Prolepsis Institute for Preventive, Environmental and Occupational Medicine

OTHER

Sponsor Role collaborator

Universitat Politècnica de València

OTHER

Sponsor Role collaborator

STICHTING INTERNATIONAL FOUNDATION FOR INTEGRATED CARE

UNKNOWN

Sponsor Role collaborator

Medical University of Lodz

OTHER

Sponsor Role collaborator

Consejería de Familia, Juventud y Política Social, Comunidad de Madrid

UNKNOWN

Sponsor Role collaborator

Servicio Madrileño de Salud, Madrid, Spain

OTHER

Sponsor Role collaborator

Fundacion para la Investigacion e Innovacion Biosanitaria de Atencion Primaria

UNKNOWN

Sponsor Role collaborator

Mental Health Europe - Sante Mentale Europe

UNKNOWN

Sponsor Role collaborator

University Mental Health Research Institute, Athens, Greece

OTHER

Sponsor Role collaborator

Fundacion para el Fomento en Asturias de la Investigacion Cientifica Aplicada y Tecnologia

UNKNOWN

Sponsor Role collaborator

Consejeria de Salud - Principado de Asturias

UNKNOWN

Sponsor Role collaborator

Servicio de Salud del Principado de Asturias

UNKNOWN

Sponsor Role collaborator

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Igor Grabovac

Project coordinator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Igor Grabovac, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Medical University of Vienna

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hietzing Hospital

Vienna, , Austria

Site Status RECRUITING

LOGIN - Verein zur Gesundheitsförderung und sozialen Integration

Vienna, , Austria

Site Status RECRUITING

Medical University of Vienna

Vienna, , Austria

Site Status RECRUITING

Mental Health Clinic

Athens, , Greece

Site Status RECRUITING

The Day Hospital

Athens, , Greece

Site Status RECRUITING

The Guest House / Protected apartments

Athens, , Greece

Site Status RECRUITING

The Association of Youth and People with Mental Problems, Their Families and Friends POMOST

Lodz, , Poland

Site Status RECRUITING

General Directorate of Social Services, council of family, youth and social affairs, community of Madrid (DGSSI-CM)

Madrid, , Spain

Site Status RECRUITING

Servicio Madrileño de Salud (SERMAS)

Madrid, , Spain

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Austria Greece Poland Spain

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Igor Grabovac, MD, PhD

Role: CONTACT

+43 1 40160 34897

Hanna M. Mües, MSc

Role: CONTACT

+43 1 40160 34662

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Igor Grabovac

Role: primary

004314016034897

Igor Grabovac

Role: primary

004314016034897

Igor Grabovac

Role: primary

004314016034897

Mental Health Clinic

Role: primary

The Day Hospital

Role: primary

The Guest House / Protected apartments

Role: primary

Magdalena Wrzesińska

Role: primary

0048693037010

Noelia Mancebo Salas

Role: primary

0034913925528

Rosa Gomez Trenado

Role: primary

0034913700942

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

101104784

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Expanding Rural Health Cancer Control Capacity
NCT04765072 ACTIVE_NOT_RECRUITING NA
Chemo Brain Prehab Project
NCT07341217 NOT_YET_RECRUITING NA