Telerehabilitation and Tele-psychological Support in Cancer Patients eCAN JA

NCT ID: NCT06007001

Last Updated: 2024-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

354 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-25

Study Completion Date

2024-09-01

Brief Summary

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The integration of teleconsultation (TC) and telemonitoring (TM) in cancer patients care may allow to improve person-centered care and patients' empowerment.

The eCAN JA explores the role of telemedicine tools (i.e. TC \& TM) in clinical trials focusing on tele-rehabilitation and tele-psychological support in different populations of cancer patients in 10 European countries. The pilots will be conducted among 354 patients affected by breast (BC, pilot 1a), head \& neck (H\&N, pilot 1b) and advanced (pilot 2) cancers.

The main aim is to assess the effect of TC and TM program focused on rehabilitation and psychological support for cancer patients on patient reported outcomes measures (PROMs) in three pilots compare to usual care.

Patients will be randomly assigned either to the intervention or control groups using a 1:1 ratio. Patients in the intervention group will receive weekly TC of 30 minutes during 8 weeks through the secure Edumeet platform. In pilot 1, tele-rehabilitation training will be performed by a remote physiotherapist and will consist of a series of rehabilitation exercises. In pilot 2, tele-psychological support will be performed by a remote psychologist and will consist of techniques for managing emotions and stress. In the intervention group, patients will also have the possibility to wear a smartwatch to automatically collect physical parameters. Patients in the control group will receive usual care.

PROMs (i.e. quality of life, distress and pain) and physical parameters (i.e. physical activity, sleep quality and heart rate) will be monitored by a dedicated telemonitoring systems. A secure web platform will provide dashboard to clinicians for decision support. Patients' experience and costs data will be also collected. The results of the eCAN project will improve our knowledge on benefits and risks for TC and TM in cancer patients care.

Detailed Description

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Conditions

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Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Telemedicine

Patients in the intervention group will receive weekly teleconsultation of 30 minutes during 8 weeks through the secure Edumeet platform. In pilot 1, tele-rehabilitation training will be performed by a remote physiotherapist and will consist of a series of rehabilitation exercises. In pilot 2, tele-psychological support will be performed by a remote psychologist and will consist of techniques for managing emotions and stress. In the intervention group, patients will also have the possibility to wear a smartwatch to automatically collect physical parameters.

Group Type EXPERIMENTAL

Telemedicine

Intervention Type DEVICE

Pilot 1a/b : the tele-rehabilitation intervention in BC or H\&N operated patients will consist of a series of exercises. The physiotherapist during teleconsultation rehabilitation program will explain to the patient how to perform the movements and regulate breathing. Practical advice on correct and incorrect habits will also be dispensed by the physiotherapist during the teleconsultation.

Pilot 2: the tele-rehabilitation intervention will consist of tele psychological support performed by a trained psychologist in each participating center It will consist of the learning of techniques for managing negative emotions, for relaxation and for implementing effective behavioural and coping strategies.

For each group, the TC will be scheduled every week for 8 weeks. The session will be available on a secure platform (Edumeet). Moreover, if they agree to, patients will also wear a smart watch to monitor physical parameters such as physical activity, sleeping and heart rate.

Usual care

Patients in the control group will receive usual care.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Telemedicine

Pilot 1a/b : the tele-rehabilitation intervention in BC or H\&N operated patients will consist of a series of exercises. The physiotherapist during teleconsultation rehabilitation program will explain to the patient how to perform the movements and regulate breathing. Practical advice on correct and incorrect habits will also be dispensed by the physiotherapist during the teleconsultation.

Pilot 2: the tele-rehabilitation intervention will consist of tele psychological support performed by a trained psychologist in each participating center It will consist of the learning of techniques for managing negative emotions, for relaxation and for implementing effective behavioural and coping strategies.

For each group, the TC will be scheduled every week for 8 weeks. The session will be available on a secure platform (Edumeet). Moreover, if they agree to, patients will also wear a smart watch to monitor physical parameters such as physical activity, sleeping and heart rate.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Pilot 1a: All consenting adult women, aged between 45 and 65 years old, who undergo a unilateral mastectomy plus axillary dissection for newly diagnosed breast cancer in a cancer center of participating European countries will be eligible for this study.
* Pilot 1b: All consenting adult patients, aged between 18 and 75 years old, with histopathologically proven H\&N cancer who are prescheduled for an en bloc resection of the primary tumor, neck dissection, or reconstruction in a cancer center of participating European countries will be eligible for this study.
* Pilot 2: All consenting adult patients, aged between 18 and 75 years old, affected by advanced/recurrent cancer (including lung, prostate, colorectum, breast cancer, gastric, genito-urinary) will be eligible for this study.

Exclusion Criteria

* For both study pilot 1a \& 1b: Patients are ineligible to participate if they meet one of the following criteria: (I) having breast reconstruction, (II) having blindness or severe visual impairment, (III) having life expectancy of less than 3 months, (IV) having previous upper limb injury or conditions that limit upper limb range of motion (shoulder flexion (\< 150°) or elbow extension/flexion (\< 0/145°) respectively), (V) unable to be assigned to tele-rehabilitation due to clinical conditions requiring in-person rehabilitation, (VI) unable to sign informed consent, (VII) not having access to an internet connection, (VIII) not having access to an android smartphone or (IX) already involved in other telemedicine services. For pilot 1b, H\&N cancer patients needing post-surgery radiotherapy will be excluded.
* For pilot 2: Patients are ineligible to participate if they meet one of the following criteria: (I) unable to sign informed consent; (II) present relevant cognitive deterioration; (III) performance status \> ECOG 2; (IV) previous diagnosis of major depression, the presence of mood disorders will be assessed with Personal Health Questionnaire Depression Scale (PHQ-8) (13); (V) starting antidepressant pharmacological treatment in the last 4 weeks before the enrollment; (VI) taking antipsychotic treatment, (VII) not having access to an internet connection (VIII) not having access to an android smartphone or (IX) already involved in other telemedicine services.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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European Commission

OTHER

Sponsor Role collaborator

Sciensano

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Andrea Pace, Dr

Role: PRINCIPAL_INVESTIGATOR

Neuro-Oncology Unit, Regina Elena Cancer Institute, Italy

Locations

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The Antwerp University Hospital (UZA)

Antwerp, , Belgium

Site Status NOT_YET_RECRUITING

German Oncology Center (GOC)

Ágios Athanásios, , Cyprus

Site Status RECRUITING

CUT

Limassol, , Cyprus

Site Status RECRUITING

The Bank of Cyprus Oncology Center (BOCOC)

Stróvolos, , Cyprus

Site Status RECRUITING

Aristotle University of Thessaloniki

Thessaloniki, , Greece

Site Status RECRUITING

National Institute of Oncology

Budapest, , Hungary

Site Status RECRUITING

Dr Steevens Hospital

Dublin, , Ireland

Site Status NOT_YET_RECRUITING

The National Cancer Institute of Naples (INT Pascale)

Naples, , Italy

Site Status NOT_YET_RECRUITING

The Regina Elena National Cancer Institute (IFO-IRE)

Roma, , Italy

Site Status RECRUITING

Hospital of Lithuanian University of Health Sciences Kauna Klinikos (KK)

Kaunas, , Lithuania

Site Status NOT_YET_RECRUITING

National Cancer Institute (NCI)

Vilnius, , Lithuania

Site Status NOT_YET_RECRUITING

Vilnius University Hospital Santaros Klinikos VULSK

Vilnius, , Lithuania

Site Status NOT_YET_RECRUITING

Portuguese Institute of Cancer of Coimbra (IPO)

Coimbra, , Portugal

Site Status RECRUITING

Portuguese Institute of Cancer of Lisbon (IPO)

Lisbon, , Portugal

Site Status NOT_YET_RECRUITING

Portuguese Institute of Cancer of Porto (IPO)

Porto, , Portugal

Site Status RECRUITING

The institute of Oncology Ljubljana (OIL)

Ljubljana, , Slovenia

Site Status RECRUITING

IDIVAL

Santander, , Spain

Site Status RECRUITING

Andalusian Health Service

Seville, , Spain

Site Status RECRUITING

Countries

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Belgium Cyprus Greece Hungary Ireland Italy Lithuania Portugal Slovenia Spain

Central Contacts

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Andrea Pace, Dr

Role: CONTACT

+390652666153

Victoria Leclercq, PhD

Role: CONTACT

Facility Contacts

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Timon Vandamme, Dr

Role: primary

Contantinos Zambogou

Role: primary

Angelos Kassianos, Dr

Role: primary

Anastasia Constantinidou

Role: primary

Eleni Timotheadou

Role: primary

József Lövey, Dr

Role: primary

Des OToole

Role: primary

Maria C Piccirillo

Role: primary

Andrea Pace, Dr

Role: primary

Viktoras Rudzianskas

Role: primary

Jolanta Paskeviciene

Role: primary

Marija Turlinksienė

Role: primary

Rui Soares

Role: primary

Joana Dias

Role: primary

Maria Moura

Role: backup

Otilia Romano

Role: primary

Eunice Silva

Role: backup

Cvetka Grašič Kuhar

Role: primary

Ignacio Durán

Role: primary

David Vicente

Role: primary

Other Identifiers

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eCAN pilots

Identifier Type: -

Identifier Source: org_study_id

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