Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)
NCT ID: NCT06426836
Last Updated: 2026-01-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
300 participants
INTERVENTIONAL
2016-08-19
2026-07-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Amoxicillin-clavulanate
Patients receiving amoxicillin-clavulanate as part of routine clinical care. Study procedure: blood sampling
Amoxicillin-clavulanate
blood sampling in patients receiving amoxicillin-clavulanate as part of routine clinical care
Piperacillin-tazobactam
Patients receiving piperacillin-tazobactam as part of routine clinical care. Study procedure: blood sampling
Piperacillin-tazobactam
blood sampling in patients receiving piperacillin-tazobactam as part of routine clinical care.
Meropenem
Patients receiving meropenem as part of routine clinical care. Study procedure: blood sampling
Meropenem
blood sampling in patients receiving meropenem as part of routine clinical care.
Cefazolin
Patients receiving cefazolin as part of routine clinical care. Study procedure: blood sampling
Cefazolin
blood sampling in patients receiving cefazolin as part of routine clinical care.
Vancomycin
Patients receiving vancomycin as part of routine clinical care. Study procedure: blood sampling
Vancomycin
blood sampling in patients receiving vancomycin as part of routine clinical care.
Teicoplanin
Patients receiving teicoplanin as part of routine clinical care. Study procedure: blood sampling
Teicoplanin
blood sampling in patients receiving teicoplanin as part of routine clinical care.
Ciprofloxacin
Patients receiving ciprofloxacin as part of routine clinical care. Study procedure: blood sampling
Ciprofloxacin
blood sampling and urine sampling in patients receiving ciprofloxacin as part of routine clinical care.
Amikacin
Patients receiving amikacin as part of routine clinical care. Study procedure: blood sampling
Amikacin
blood sampling in patients receiving amikacin as part of routine clinical care.
Interventions
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Teicoplanin
blood sampling in patients receiving teicoplanin as part of routine clinical care.
Ciprofloxacin
blood sampling and urine sampling in patients receiving ciprofloxacin as part of routine clinical care.
Amikacin
blood sampling in patients receiving amikacin as part of routine clinical care.
Vancomycin
blood sampling in patients receiving vancomycin as part of routine clinical care.
Amoxicillin-clavulanate
blood sampling in patients receiving amoxicillin-clavulanate as part of routine clinical care
Piperacillin-tazobactam
blood sampling in patients receiving piperacillin-tazobactam as part of routine clinical care.
Meropenem
blood sampling in patients receiving meropenem as part of routine clinical care.
Cefazolin
blood sampling in patients receiving cefazolin as part of routine clinical care.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* patient age : 1,8 kg-15 years
* patient receiving antibiotic treatment (piperacillin-tazobactam, meropenem, amoxicillin-clavulanate, cephazolin, vancomycin, teicoplanin, ciprofloxacin, amikacin)
* intra-arterial or intravenous access other than the drug infusion line available for blood sampling (arterial line is preferred)
* extracorporeal membrane oxygenation circuit
Exclusion Criteria
* absence of parental/patient consent
* known hypersensitivity to beta-lactam antibiotics and ciprofloxacin
15 Years
ALL
No
Sponsors
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University Hospital, Ghent
OTHER
Responsible Party
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Principal Investigators
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Annick de Jaeger, MD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Ghent
Locations
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Queen Fabiola Children's University Hospital
Brussels, Brussels Capital, Belgium
University Hospital
Ghent, , Belgium
Universitair hospital
Leuven, , Belgium
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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EC 2015/0529
Identifier Type: -
Identifier Source: org_study_id
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