Characterization of Left Atrial Substrate in Patients With Ventricular Arrhythmias
NCT ID: NCT06425822
Last Updated: 2024-05-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
50 participants
OBSERVATIONAL
2023-11-08
2027-10-31
Brief Summary
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The main questions it aims to answer are:
* Are the left atrial electroanatomical changes a consequence or a precursor to the development of atrial fibrillation?
* Are the left atrial electroanatomical findings different between patients with atrial fibrillation and those at high risk of developing it?
* What is the prognostic impact of left atrial pathologic changes in patients without diagnosed atrial fibrillation in terms of cardiovascular outcomes?
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Left atrial mapping group in patients without atrial fibrillation
Inclusion criteria:
* Age ≥ 18 years old.
* Absence of a prior history of atrial fibrillation or flutter.
* Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2.
Exclusion criteria:
* Presence of thrombus in the left atrial appendage.
* Complications related to the index procedure.
* Insufficient quality of the left atrial electroanatomical map.
Left atrial electroanatomical mapping
Left atrial electroanatomical mapping (substrate and functional mapping)
Interventions
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Left atrial electroanatomical mapping
Left atrial electroanatomical mapping (substrate and functional mapping)
Eligibility Criteria
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Inclusion Criteria
* Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2.
Exclusion Criteria
* Complications related to the index procedure.
* Insufficient quality of the left atrial electroanatomical map.
18 Years
ALL
No
Sponsors
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Universitair Ziekenhuis Brussel
OTHER
Responsible Party
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Andrea Sarkozy
Clinical Professor
Principal Investigators
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Andrea Sarkozy, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Universitair Ziekenhuis Brussel
Locations
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Universitair Ziekenhuis Brussel
Jette, Brussels Capital, Belgium
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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EC-2023-281
Identifier Type: -
Identifier Source: org_study_id
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