Monitoring of Non-Surgical Treatment of Peri-implantitis

NCT ID: NCT06408467

Last Updated: 2024-05-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-01

Study Completion Date

2022-11-15

Brief Summary

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This study aimed to investigate the response to non-surgical treatment of peri-implantitis diseases during the maintenance phase. The patients underwent non-surgical implant maintenance treatment, and the success of the treatment was measured again after 30 days using the same criteria and methods.

Detailed Description

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For 40 patients, the aMMP-8 test was performed on the buccal gingival pocket of the implant teeth, gingival bleeding (BOP), implant pocket depth (PPD), and a periapical x-ray to measure radiologic bone level (RBL) were taken.

Conditions

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Peri-implant Mucositis Peri-Implantitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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The effect and monitoring of maintenance therapy for peri-implantitis

Group Type EXPERIMENTAL

aMMP-8 diagnostic test

Intervention Type OTHER

40 patients

Interventions

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aMMP-8 diagnostic test

40 patients

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* implant patients arriving for a maintenance visit at a dental clinic
* a diagnosis of peri-implant healthy, peri-implant mucositis, or peri-implantitis by a dentist
* a written informed consent.

Exclusion Criteria

* Smoking
* age under 25
* antibiotic treatment within six months
* the maintenance treatment had been completed within 6 months.
Minimum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Helsinki

OTHER

Sponsor Role collaborator

Lahanna oy

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Timo Sorsa, Professor

Role: STUDY_DIRECTOR

University of Helsinki

Locations

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University of Helsinki

Helsinki, , Finland

Site Status

Countries

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Finland

References

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Lindhe J, Meyle J; Group D of European Workshop on Periodontology. Peri-implant diseases: Consensus Report of the Sixth European Workshop on Periodontology. J Clin Periodontol. 2008 Sep;35(8 Suppl):282-5. doi: 10.1111/j.1600-051X.2008.01283.x.

Reference Type RESULT
PMID: 18724855 (View on PubMed)

Figuero E, Graziani F, Sanz I, Herrera D, Sanz M. Management of peri-implant mucositis and peri-implantitis. Periodontol 2000. 2014 Oct;66(1):255-73. doi: 10.1111/prd.12049.

Reference Type RESULT
PMID: 25123773 (View on PubMed)

Lahteenmaki H, Umeizudike KA, Heikkinen AM, Raisanen IT, Rathnayake N, Johannsen G, Tervahartiala T, Nwhator SO, Sorsa T. aMMP-8 Point-of-Care/Chairside Oral Fluid Technology as a Rapid, Non-Invasive Tool for Periodontitis and Peri-Implantitis Screening in a Medical Care Setting. Diagnostics (Basel). 2020 Aug 5;10(8):562. doi: 10.3390/diagnostics10080562.

Reference Type RESULT
PMID: 32764436 (View on PubMed)

Alassy H, Parachuru P, Wolff L. Peri-Implantitis Diagnosis and Prognosis Using Biomarkers in Peri-Implant Crevicular Fluid: A Narrative Review. Diagnostics (Basel). 2019 Dec 7;9(4):214. doi: 10.3390/diagnostics9040214.

Reference Type RESULT
PMID: 31817894 (View on PubMed)

Other Identifiers

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Lahanna

Identifier Type: -

Identifier Source: org_study_id

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