Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy
NCT ID: NCT06388486
Last Updated: 2024-04-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
63 participants
OBSERVATIONAL
2017-01-01
2024-01-01
Brief Summary
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* Do psychological traits (i.e.: social inhibition, negative affectivity, ...) affect the activation of immunomodulatory transcription factors (STAT3, NFkB) in depressed patients?
* Are subjects with these psychological traits affected differently by psychotherapeutic intervention?
Study subjects are assessed for their psychological and behavioral traits and receive psychotherapeutic care over several weeks during hospital treatment. Peripheral blood mononuclear cells are isolated from the study subjects, and activation of transcription factors is measured by flow cytometry.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Psychotherapy
Subject receive psychotherapy during hospital treatment.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* unable to give informed consent
* severe psychiatric comorbidities, such as drug abuse and psychotic diseases
* deemed critically unstable by their treating physician
18 Years
ALL
No
Sponsors
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University Medical Center Goettingen
OTHER
Responsible Party
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Prof. Thomas Meyer
Clinical Professor, Head of the Molecular Psychocardiology laboratory
Other Identifiers
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UMCGoettingen9/9/16
Identifier Type: -
Identifier Source: org_study_id
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