The Efficacy of Radiomics to Predict Tumor Microenvironment Markers and Comprehensive Therapy for Bladder Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-30

Study Completion Date

2024-02-20

Brief Summary

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The aim of this study was to develop an radiomic model based on CT images to evaluate markers of the bladder cancer microenvironment, such as TSR,TIL, and IP. Secondly, the association of the radiomic model with clinical outcomes and immunotherapy response was investigated.

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Detailed Description

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Conditions

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Bladder Cancer Radiomics Immunotherapy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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1

Sun Yat-sen Memorial Hospital cohort

No interventions assigned to this group

2

Third Affiliated Hospital of Sun Yat-sen University cohort

No interventions assigned to this group

3

Sun Yat-sen University Cancer Center cohort

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. At least 18 years of age;
2. Performing TURB-t or RC during 2010-2022;
3. The primary lesion was located in the bladder, and the pathological diagnosis was urothelial carcinoma;
4. Complete clinical information, pathological data, preoperative pelvic enhanced CT and follow-up records;

Exclusion Criteria

1. Patients with distant metastasis;
2. Combined with other malignant tumors or malignant tumor treatment history
3. Malignant tumors of upper urinary tract;
4. Clinical information, pathological data, preoperative pelvic enhanced CT and follow-up records were missing;
5. Other situations in which the researcher considers it inappropriate to participate in this study.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No