Multicenter, Interdisciplinary National VEXAS Registry With Accompanying Biomaterial Collection

NCT ID: NCT06377462

Last Updated: 2025-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-13

Study Completion Date

2030-12-31

Brief Summary

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The aim is rapid collection of real-life data on the epidemiology, treatment and disease course in patients with VEXAS syndrome during routine clinical practice and collect biomaterials to evaluate genotype-phenotype associations, determine optimal treatment schedule, identify diagnostic features and biomarkers

Detailed Description

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see brief summary

Conditions

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VEXAS Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients with established or suspected (clinical and hematological criteria) VEXAS Syndrome
* Age ≥18 years
* Signed informed consent form

Exclusion Criteria

* patients who are not in a position to understand the nature and scope of participation in this register
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bristol-Myers Squibb

INDUSTRY

Sponsor Role collaborator

University Hospital Munich

OTHER

Sponsor Role collaborator

Technische Universität Dresden

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Katja Sockel, Dr. med.

Role: STUDY_CHAIR

TU Dresden

Locations

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Universitätsklinikum Aachen

Aachen, , Germany

Site Status RECRUITING

Klinikum Chemnitz gGmbH

Chemnitz, , Germany

Site Status RECRUITING

Universitätsklinikum Carl Gustav Carus

Dresden, , Germany

Site Status RECRUITING

Universitätsklinikum Düsseldorf

Düsseldorf, , Germany

Site Status RECRUITING

Evang. Kliniken Essen-Mitte

Essen, , Germany

Site Status RECRUITING

Universitätsklinikum Hamburg-Eppendorf

Hamburg, , Germany

Site Status RECRUITING

Universitätsklinikum Leipzig AöR

Leipzig, , Germany

Site Status RECRUITING

Universitätsmedizin Mannheim

Mannheim, , Germany

Site Status RECRUITING

Klinikum rechts der Isar TUM

München, , Germany

Site Status RECRUITING

Klinikum Osnabrück GmbH

Osnabrück, , Germany

Site Status RECRUITING

Helios Kliniken Schwerin GmbH

Schwerin, , Germany

Site Status RECRUITING

Robert Bosch Gesellschaft für Medizinische Forschung mb

Stuttgart, , Germany

Site Status RECRUITING

Krankenhaus der Barmherzigen Brüder

Trier, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Katja Sockel, Dr. med.

Role: CONTACT

+493514585627

Katharina Goetze, Prof.

Role: CONTACT

+498941404618

Facility Contacts

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Katja Sockel, Dr. med.

Role: primary

Related Links

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https://vexas.net/

Website VEXAS Registry

Other Identifiers

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VEXAS-Registry

Identifier Type: -

Identifier Source: org_study_id

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