Investigation of the Detection Rate of Pathogenic Viruses in the Feces of Individuals With Non-gastrointestinal Infections

NCT ID: NCT06367647

Last Updated: 2024-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-05-04

Study Completion Date

2025-12-31

Brief Summary

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This project is a cross-sectional study. Investigators plan to search and collect 1600 publicly published fecal metagenomic and metatranscriptome data through the Pubmed database, by summarizing and analyzing them to construct an enterovirus database. 200 apparently healthy individuals are planned to be enrolled. At the time of enrollment, fecal specimens of participants will be collected, and their demographic characteristics, disease and medication history, gastrointestinal status, dietary habits, lifestyle habits, and mental health information will be recorded. Another 200 specimens will be collected from patients with parenteral virus infection. The demographic characteristics and pathogen test results of the parenteral virus infected patients will be reviewed and recorded. By virus metagenomic sequencing on fecal specimens, investigators will identify which viruses can be detected in the intestinal tract of apparently healthy people, and to explore whether parenteral infection viruses can be detected in feces.

Detailed Description

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Conditions

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Virus Infections

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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apparently healthy individuals

No interventions assigned to this group

parenteral virus infected patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. age ranged from 18 to 75 years;
2. no obvious symptoms and signs of the disease;
3. not taking a drug for a long time;
4. good psychological condition ;
5. no unhealthy lifestyle;
6. willing to participate in the study, sign the informed consent, fill out the questionnaire and provide fecal samples.

Exclusion Criteria

1. pregnant and lactating women;
2. suffering from certain diseases, such as cardiovascular disease, digestive system disease and nervous system disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zhujiang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yan He

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yan He, Doctor

Role: PRINCIPAL_INVESTIGATOR

Southern Medical University, China

Locations

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Zhujiang hospital of southern medical university

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yumei Liu, master

Role: CONTACT

+8618810795365

Facility Contacts

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Yumei Liu, master

Role: primary

+8618810795365

Other Identifiers

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zhujiangjy-20240229

Identifier Type: -

Identifier Source: org_study_id

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