Effect of Coffee Consumption on Pain and Intestinal Motility After Caesarean Section:

NCT ID: NCT06359223

Last Updated: 2025-07-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

57 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-20

Study Completion Date

2024-12-30

Brief Summary

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Objective The aim of this study was to investigate whether postoperative coffee intake affects pain levels and bowel motility in women undergoing cesarean delivery.

Design: It will be conducted as a randomized controlled experimental study. Method: It is a randomized controlled experimental study: This randomized controlled clinical trial will be conducted between May and December 2024 in accordance with the Consolidated Standards of Reporting Trials. A total of 60 women will be randomly assigned to the intervention group (n=30) or the control group (n=30). Participants in the intervention group will receive 100 mg caffeine in coffee at 6 and 12 hours after surgery in addition to routine postoperative care. The control group will receive only routine postoperative care. Pain will be assessed using Visual Analog Scale (VAS) and bowel activity will be monitored by time to first defecation, gas passage and bowel sounds.

Keywords: Caesarean section, Coffee, Pain, Motility

Detailed Description

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Conditions

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Operation Cesarean Section

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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caffeine group

Participants in the intervention group will receive 100 mg caffeine in coffee at 6 and 12 hours after surgery in addition to routine postoperative care. The control group will receive only routine postoperative care. Pain will be assessed using Visual Analog Scale (VAS) and bowel activity will be monitored by time to first defecation, gas passage and bowel sounds.

Group Type EXPERIMENTAL

coffee consumption

Intervention Type DIETARY_SUPPLEMENT

After cesarean section, patients will be allowed to drink coffee.

control group

The control group will receive only routine postoperative care. Pain will be assessed using Visual Analog Scale (VAS) and bowel activity will be monitored by time to first defecation, gas passage and bowel sounds.

Group Type ACTIVE_COMPARATOR

control group

Intervention Type OTHER

Patients will undergo a routine surgical procedure.

Interventions

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coffee consumption

After cesarean section, patients will be allowed to drink coffee.

Intervention Type DIETARY_SUPPLEMENT

control group

Patients will undergo a routine surgical procedure.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* had a cesarean delivery with spinal anesthesia,
* had a postoperative pain level of 4 or higher,
* could read and write Turkish,
* could communicate effectively with the researchers.

Exclusion Criteria

* Those who underwent emergency cesarean section,
* Those with pregnancy complications (e.g., preeclampsia, gestational diabetes, placenta previa),
* Those with a history of chronic gastrointestinal disease (e.g., irritable bowel syndrome, Crohn's disease, ulcerative colitis),
* Those with caffeine sensitivity or allergy,
* Those with chronic pain syndrome or analgesic dependence,
* Those who regularly consume coffee (≥2 cups per day),
* Those who experienced intraoperative complications (e.g., bowel or bladder injury),
* Those who could not comply with the study protocol.
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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KTO Karatay University

OTHER

Sponsor Role collaborator

TC Erciyes University

OTHER

Sponsor Role lead

Responsible Party

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HÜMEYRA YÜKSEL

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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HÜMEYRA YÜKSEL, Phd

Role: PRINCIPAL_INVESTIGATOR

KTO Karatay University

Locations

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KTO Karatay Unıversty

Konya, Karatay, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Zamanabadi MN, Alizadeh R, Gholami F, Seyed Mehdi SA, Aryafar M. Effect of caffeine on postoperative bowel movement and defecation after cesarean section. Ann Med Surg (Lond). 2021 Aug 6;68:102674. doi: 10.1016/j.amsu.2021.102674. eCollection 2021 Aug.

Reference Type BACKGROUND
PMID: 34401138 (View on PubMed)

Abadi F, Shahabinejad M, Abadi F, Kazemi M. Effect of Acupressure on Symptoms of Postoperative Ileus After Cesarean Section. J Acupunct Meridian Stud. 2017 Apr;10(2):114-119. doi: 10.1016/j.jams.2016.11.008. Epub 2016 Dec 27.

Reference Type BACKGROUND
PMID: 28483182 (View on PubMed)

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Reference Type BACKGROUND

Goymen, A., Simsek, Y., Ozkaplan, S. E., Ozdurak, H. I., Akpak, Y. K., Semiz, A., & Oral, S. (2017). Effect of gum chewing and coffee consumption on intestinal motility in caesarean sections.

Reference Type RESULT

Tian YT. 2017. China is not"The World's First Cesarean Section Rate".Beijing: Guangming Daily.

Reference Type RESULT

Curran EA, Khashan AS, Dalman C, Kenny LC, Cryan JF, Dinan TG, Kearney PM. Obstetric mode of delivery and attention-deficit/hyperactivity disorder: a sibling-matched study. Int J Epidemiol. 2016 Apr;45(2):532-42. doi: 10.1093/ije/dyw001. Epub 2016 Apr 10.

Reference Type RESULT
PMID: 27063604 (View on PubMed)

Khadem N, Khadivzadeh T. The intelligence quotient of school aged children delivered by cesarean section and vaginal delivery. Iran J Nurs Midwifery Res. 2010 Summer;15(3):135-40.

Reference Type RESULT
PMID: 21589777 (View on PubMed)

Souza JP, Betran AP, Dumont A, de Mucio B, Gibbs Pickens CM, Deneux-Tharaux C, Ortiz-Panozo E, Sullivan E, Ota E, Togoobaatar G, Carroli G, Knight H, Zhang J, Cecatti JG, Vogel JP, Jayaratne K, Leal MC, Gissler M, Morisaki N, Lack N, Oladapo OT, Tuncalp O, Lumbiganon P, Mori R, Quintana S, Costa Passos AD, Marcolin AC, Zongo A, Blondel B, Hernandez B, Hogue CJ, Prunet C, Landman C, Ochir C, Cuesta C, Pileggi-Castro C, Walker D, Alves D, Abalos E, Moises E, Vieira EM, Duarte G, Perdona G, Gurol-Urganci I, Takahiko K, Moscovici L, Campodonico L, Oliveira-Ciabati L, Laopaiboon M, Danansuriya M, Nakamura-Pereira M, Costa ML, Torloni MR, Kramer MR, Borges P, Olkhanud PB, Perez-Cuevas R, Agampodi SB, Mittal S, Serruya S, Bataglia V, Li Z, Temmerman M, Gulmezoglu AM. A global reference for caesarean section rates (C-Model): a multicountry cross-sectional study. BJOG. 2016 Feb;123(3):427-36. doi: 10.1111/1471-0528.13509. Epub 2015 Aug 10.

Reference Type RESULT
PMID: 26259689 (View on PubMed)

Tuzmen HD, Yuksel H, Yazar M, Sayar S, Horasanli JE. The effect of coffee consumption on postoperative pain and bowel motility following cesarean section: a randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2025 Nov;314:114723. doi: 10.1016/j.ejogrb.2025.114723. Epub 2025 Sep 13.

Reference Type DERIVED
PMID: 40967073 (View on PubMed)

Other Identifiers

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2400602

Identifier Type: -

Identifier Source: org_study_id

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