Atrial Fibrillation, Prevention and Rehabilitation

NCT ID: NCT06337045

Last Updated: 2024-03-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-01

Study Completion Date

2020-06-30

Brief Summary

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Evidence shows that people with atrial fibrillation (AF) can benefit from prevention and rehabilitation interventions related to quality of life, lowered anxiety, etc. In this study, a complex prevention and rehabilitation intervention for people with AF was carried out in a Health Center at a Danish municipality in cooperation with the cardiology department at Svendborg Hospital. The study was designed as a feasibility study, with data gathered systematically including focus group interviews and quantitative patient reported outcomes. People with AF were included at the hospital. Eligible participants were offered intervention in the Health Center. Interventions, in accordance with present international guidelines, consisted of physical exercise, patient education, psychosocial support and consultations with health professionals as well as risk factor management. Also, medicinal yoga (MediYoga) were chosen to be part of the intervention due to promising research results within AF. All interventions were optional and based on needs assessment and preferences.

The primary objective was to investigate the feasibility of delivering a complex prevention and rehabilitation intervention for people with AF in a municipal Health Center.

There were the following four secondary objectives:

1. To explore the participant's experiences of participating in the municipality-based complex prevention and rehabilitation intervention.
2. To explore the participant's needs and preferences of the interventions.
3. To explore changes in HRQoL, anxiety and depression.
4. To explore the feasibility of collecting patient reported outcome measures as part of the intervention.

The hypothesis was that the complex prevention and rehabilitation intervention was feasible in a municipality-based set-up, and was well received by people with AF and may contribute to better outcomes in terms of HRQoL, anxiety and depression.

Detailed Description

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Conditions

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Atrial Fibrillation Prevention Rehabilitation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Eligible participants were diagnosed with AF at the hospital and had symptomatic AF rated by the modified European Heart Rhythm Association (mEHRA) score ≥2B. If the patient was eligible based on the mEHRA-score, at least one of the following risk factors had to be present: hypertension, diabetes, obesity, smoking, excessive alcohol consumption, physical inactivity, sleep apnoea, anxiety, depression, or mental vulnerability.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Complex prevention and rehabilitation intervention (single arm)

It was a single-arm study.

Group Type EXPERIMENTAL

Complex prevention and rehabilitation intervention

Intervention Type BEHAVIORAL

The complex intervention started and ended with individual consultations with health professionals and furthermore included physical exercise, smoking cessation, alcohol treatment, dietary interventions, AF specific patient education, MediYoga, and/or psychosocial support.

Interventions

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Complex prevention and rehabilitation intervention

The complex intervention started and ended with individual consultations with health professionals and furthermore included physical exercise, smoking cessation, alcohol treatment, dietary interventions, AF specific patient education, MediYoga, and/or psychosocial support.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* the modified European Heart Rhythm Association (mEHRA) score ≥2B.

And at least one of the following risk factors:

* Hypertension (treatment with \>1 drug, diagnosis verified by home-blood pressure measurement, 24-hour ambulatory blood pressure measurement, or consultation blood pressure measurement \>160/90mmHg).
* Diabetes mellitus (HbA1c \> 58mmol/mol unless higher values are accepted due to other aspects).
* Obesity (Body Mass Index \> 30).
* Smoking (active smoker).
* Alcohol consumption (\> 7 units per week for women and \> 14 units per week for men (according to the Danish Health Authority guidelines from 2019), or motivation for reduction).
* Physical inactivity (less than the recommended 30 minutes per day).
* Known sleep apnea or STOP-bang Sleep Apnea Questionnaire score \>3).
* Symptoms of anxiety or depression evaluated by the Hospital Anxiety and Depression Scale (HADS) \> 7.
* Mental vulnerability defined as self-evaluated burdened life with high perceived stress, small social network, and/or low educational level.

Exclusion Criteria

* ongoing treatment adjustments due to heart failure.
* ongoing cardiac rehabilitation.
* dementia, mental illness, language barrier or comorbidity that made it impossible to participate in this study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Department of Cardiology, Odense University Hospital, Odense, Denmark.

UNKNOWN

Sponsor Role collaborator

Health Center, Municipality of Svendborg, Svendborg, Denmark.

UNKNOWN

Sponsor Role collaborator

Department of Internal Medicine & Emergency Department, Svendborg Hospital, Odense University Hospital, Svendborg, Denmark.

UNKNOWN

Sponsor Role collaborator

The Danish Heart Association, Funen, and local committee in Svendborg, Denmark

UNKNOWN

Sponsor Role collaborator

Odense University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Cardiology, Odense University Hospital

Odense, Region Syddanmark, Denmark

Site Status

Health Center, Municipality Svendborg

Svendborg, Region Syddanmark, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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AF-rehab

Identifier Type: -

Identifier Source: org_study_id

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