Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis
NCT ID: NCT06318598
Last Updated: 2025-05-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
200 participants
OBSERVATIONAL
2023-04-11
2026-04-10
Brief Summary
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* Which set of biomarkers explain genotypic-phenotypic correlations in ALS?
* Which set of biomarkers can be used to subdivide the ALS population in homogeneous subgroups?
Participants will undergo:
* neurological evaluation
* neurophysiological evaluation
* neuropsychological evaluation
* whole exome sequencing
* biomarker measurement in CSF and plasma
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* residence near the study centers
Exclusion Criteria
* unable/unwilling to perform follow-up visits
18 Years
ALL
No
Sponsors
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A.O.U. Città della Salute e della Scienza
OTHER
Ospedale San Raffaele
OTHER
Istituto Auxologico Italiano
OTHER
Responsible Party
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Locations
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Ospedale San Raffaele
Milan, MI, Italy
Ospedale San Luca
Milan, MI, Italy
AOU Città della Salute e della Scienza
Torino, TO, Italy
Countries
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Central Contacts
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Facility Contacts
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Yuri Falzone, MD, PhD
Role: primary
Adriano Chiò, MD
Role: primary
Other Identifiers
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23M202
Identifier Type: -
Identifier Source: org_study_id
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