Impact of Cannabis Consumption on the Course, Modalities of Hospitalization and the Short-term Prognosis of Inpatients Suffering From Psychotic Symptoms

NCT ID: NCT06314204

Last Updated: 2024-03-15

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2016-09-20
• Study Completion Date: 2026-09-06

Brief Summary

Few studies have evaluated, in patients with symptomatology the impact of cannabis use on the duration of hospitalization and on short- and medium-term developments. The objective of this study will be to assess the impact of cannabis on the duration, the hospitalization and the short- and medium-term evolution of patients with psychotic symptoms and cannabis use. We hypothesize that these patients (in comparison with patients with psychotic symptomatology and not using cannabis) would be hospitalized more long, exposed to a higher risk of resistance to the usual therapeutics, would have a lack of therapeutic alliance and insight, relapses and hospitalizations more frequent, more marked negative symptoms and lower quality remission. They would also be more prone to impulsive and aggressive behaviour.

Detailed Description

Several studies have reported that cannabis use worsen the prognosis of psychiatric pathologies in general and psychotic in particular.

Few or no studies have evaluated the impact of cannabis consumption on patients with psychotic symptoms during their hospitalization (duration, type of hospitalization, quality of relationship with staff hospital), and on the short-term prognosis.

The objective of this study will be to assess the impact of cannabis on the duration of the hospitalization and the short- and medium-term evolution of patients with a psychotic symptomatology and cannabis use. Making the hypothesis that these patients (compared to patients with symptomatology psychotic and not using cannabis) would be hospitalized longer, exposed at a higher risk of resistance to the usual therapies, to have a lack of alliance therapeutic and insight, relapses and more frequent hospitalizations and symptoms.

They would also be more likely to have lower quality. They would also be more likely to be impulsive, and have aggressive behaviours.

Conditions

Psychotic; Disorder, Cannabis

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Hospitalized in psychiatry regardless of the mode of hospitalization
• With or without protective measures (guardianship or curatorship)
• Presenting psychotic symptoms (schizophrenia, schizo affective disorder, thymic disorder with psychotic characteristic, psychotic disorder substance-induced, brief psychotic disorder, schizophrenic disorders, delirious disorders)
• Members of the social security system
• Enlightened information

Exclusion Criteria

• Degenerative neurological pathologies or mental retardation
• Psychotic disorders secondary to generalized medical conditions(epilepsy, delirium tremens, tumors, etc.)
• Other psychiatric pathologies

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Centre hospitalier de Ville-Evrard, France

OTHER

Sponsor Role: lead

Responsible Party

Noomane Bouaziz, MD

MBBS, psychiatrist and investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

unité de recherche clinique de l'E.P.S de Ville Evrard

Neuilly-sur-Marne, , France

Site Status: RECRUITING

Countries

France

Central Contacts

RUSHEENTHIRA THAVASEELAN, MSc

Role: CONTACT

r.thavaseelan@epsve.fr

0143083232

Facility Contacts

Rusheenthira THAVASEELAN, Msc

Role: primary

r.thavaseelan@epsve.fr

0143093232

Other Identifiers

2015-A01222-47

Identifier Type: -

Identifier Source: org_study_id