De Quervain's Disease in the Acute Phase:a Study Aimed at Evaluating the Effectiveness of Standard Physiotherapy Treatment (HANDGUIDE), Compared to Experimental Treatment After Performing Ultrasound-guided Infiltrative Therapy.

NCT ID: NCT06296472

Last Updated: 2025-04-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

134 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-27

Study Completion Date

2026-12-30

Brief Summary

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The objective of the study is to compare pain reduction and disability reduction in two groups of patients diagnosed with de Quervain syndrome who will undergo ultrasound-guided infiltrative treatment with corticosteroid as per normal clinical practice:

* the control group will subsequently be subjected to a standard treatment based on the European guidelines of the HANDGUIDE group,
* the experimental group will subsequently carry out a program of eccentric exercises.

Detailed Description

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Conditions

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De Quervain Disease Hand Tenosynovitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Standard

Group Type ACTIVE_COMPARATOR

Standard

Intervention Type OTHER

-the standard group will carry out a program of generic exercises following the infiltration and will also wear the wrist brace for 4 weeks.

Experimental

Group Type EXPERIMENTAL

Rehabilitation

Intervention Type OTHER

-the experimental group will carry out a program of eccentric exercises following the infiltration and will also wear the wrist brace for 4 weeks.

Interventions

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Rehabilitation

-the experimental group will carry out a program of eccentric exercises following the infiltration and will also wear the wrist brace for 4 weeks.

Intervention Type OTHER

Standard

-the standard group will carry out a program of generic exercises following the infiltration and will also wear the wrist brace for 4 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients of both sexes with a minimum age of 18 years;
* Medical diagnosis of de Quervain syndrome assessed through orthopedic clinical examination e confirmation by ultrasound;
* Signing of the informed consent and participation in the study.

Exclusion Criteria

* Patients who are not self-sufficient or not able to understand and want;
* Presence of other pathologies in the hand affected by de Quervain pathology, such as intersection syndrome, neuropathies, fractures, rhizoarthrosis, arthrosis of the radio-carpal or intercarpal joint, intercarpal instability, cervical radiculopathy, rheumatic or metabolic pathologies;
* Pregnant or breastfeeding women.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Ortopedico Rizzoli

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Istituto Ortopedico Rizzoli

Bologna, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Federico Pilla, MD

Role: CONTACT

0516366 ext. 6926

Fabio Vita, MD

Role: CONTACT

0516366 ext. 6926

Facility Contacts

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Fabio Vita, MD

Role: primary

References

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Wolf JM, Sturdivant RX, Owens BD. Incidence of de Quervain's tenosynovitis in a young, active population. J Hand Surg Am. 2009 Jan;34(1):112-5. doi: 10.1016/j.jhsa.2008.08.020. Epub 2008 Dec 10.

Reference Type RESULT
PMID: 19081683 (View on PubMed)

Walker-Bone K, Palmer KT, Reading I, Coggon D, Cooper C. Prevalence and impact of musculoskeletal disorders of the upper limb in the general population. Arthritis Rheum. 2004 Aug 15;51(4):642-51. doi: 10.1002/art.20535.

Reference Type RESULT
PMID: 15334439 (View on PubMed)

Ferrara PE, Codazza S, Cerulli S, Maccauro G, Ferriero G, Ronconi G. Physical modalities for the conservative treatment of wrist and hand's tenosynovitis: A systematic review. Semin Arthritis Rheum. 2020 Dec;50(6):1280-1290. doi: 10.1016/j.semarthrit.2020.08.006. Epub 2020 Aug 29.

Reference Type RESULT
PMID: 33065423 (View on PubMed)

Other Identifiers

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MDQ23

Identifier Type: -

Identifier Source: org_study_id

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