The Effect of Patient Position Changes on Advanced Cardiac Indices in Cancer Surgery

NCT ID: NCT06293391

Last Updated: 2024-11-07

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 80 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-02-01
• Study Completion Date: 2024-02-05

Brief Summary

Esophageal Doppler Monitoring (Deltex CardioQ Esophageal Doppler Monitor, ODM) is used to manage patients' fluid therapy by non-invasively measuring continuous cardiac output with an esophageal probe. The aim of this study was to compare the effects of patient position changes on cardiac indices and vital signs in patients who underwent major abdominal cancer surgery with laparoscopic and open surgery using ODM.

Detailed Description

Patients who underwent major abdominal cancer surgery using ODM in the operating room of our hospital between November 2021 and November 2022 were identified from the Anesthesiology Clinic records and examined according to whether they were operated with open or closed (laparoscopic) methods. Demographic data, vital signs, amount of bleeding, type and amount of fluid administered, and the results of cardiac index measurements performed with the ODM device in the supine and trendelenburg positions (45 degrees) were analyzed. Parameters recorded with the ODM device; CO: Cardiac output, FTc: Flow time corrected, PV: Peak velocity, SD: Stroke distance.

Conditions

Abdominal Cancer; Blood Pressure; Cardiac Indices

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: RETROSPECTIVE

Study Groups

ODM measurements of patients undergoing open surgery in supine and trendelenburg position

After intubation, serial ODM measurements were performed in the supine and trendelenburg position of the patient and CO: Cardiac output, FTc: Flow time corrected, PV: Peak velocity, SD: Stroke distance values were recorded.

cardiac indices in supine and trendelenburg position

Intervention Type: PROCEDURE

Cardiac indices in supine and trendelenburg position in patients undergoing open or laparoscopic major cancer surgery

ODM measurements of patients undergoing laparoscopic surgery in supine and trendelenburg position

After intubation, serial ODM measurements were performed in the supine and trendelenburg position of the patient and CO: Cardiac output, FTc: Flow time corrected, PV: Peak velocity, SD: Stroke distance values were recorded.

cardiac indices in supine and trendelenburg position

Intervention Type: PROCEDURE

Cardiac indices in supine and trendelenburg position in patients undergoing open or laparoscopic major cancer surgery

Interventions

cardiac indices in supine and trendelenburg position

Cardiac indices in supine and trendelenburg position in patients undergoing open or laparoscopic major cancer surgery

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Elective operation
• ASA 1-4

Exclusion Criteria

• Heart failure
• Valvular heart disease,
• Patients with symptomatic rhythm disturbances
• ODM placement contraindicated (coagulopathy, oesophageal varices, known aortic aneurysm)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 99 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

Mustafa Kemal ŞAHİN

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Mustafa Kemal SAHIN, M.D

Role: PRINCIPAL_INVESTIGATOR

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Locations

Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital

Ankara, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

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Reference Type: RESULT

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Yonis H, Bitker L, Aublanc M, Perinel Ragey S, Riad Z, Lissonde F, Louf-Durier A, Debord S, Gobert F, Tapponnier R, Guerin C, Richard JC. Change in cardiac output during Trendelenburg maneuver is a reliable predictor of fluid responsiveness in patients with acute respiratory distress syndrome in the prone position under protective ventilation. Crit Care. 2017 Dec 5;21(1):295. doi: 10.1186/s13054-017-1881-0.

Reference Type: RESULT

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Reference Type: RESULT

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Reference Type: RESULT

PMID: 23549128 (View on PubMed)

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Reference Type: RESULT

PMID: 24358000 (View on PubMed)

Huang L, Critchley LA. An assessment of two Doppler-based monitors to track cardiac output changes in anaesthetised patients undergoing major surgery. Anaesth Intensive Care. 2014 Sep;42(5):631-9. doi: 10.1177/0310057X1404200514.

Reference Type: RESULT

PMID: 25233178 (View on PubMed)

Argun G, Sahin MK. The impact of patient position changes on advanced hemodynamic indices in laparoscopic and open major abdominal cancer surgeries: retrospective study. BMC Surg. 2025 Aug 6;25(1):341. doi: 10.1186/s12893-025-03064-8.

Reference Type: DERIVED

PMID: 40770328 (View on PubMed)

Other Identifiers

2022-11/2097

Identifier Type: -

Identifier Source: org_study_id