Comparıson Of Electromyography Results Before And After Vıtamın D Treatment In Patıents Wıth Carpal Tunnel Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

87 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-30

Study Completion Date

2022-08-30

Brief Summary

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Therefore, we aimed to evaluate the effectiveness of vitamin D replacement therapy on pain, electrophysiological parameters, ultrasonographic measurement results and functional status scales in CTS patients with low serum vitamin D levels.

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Detailed Description

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Introduction: Apart from its effect on bone health, vitamin D is also known to have beneficial effects on the neurological system. In studies, vitamin D levels were found to be low in patients with Carpal Tunnel Syndrome (CTS). However, studies examining the effects of vitamin D replacement on CTS are limited. Therefore, we aimed to evaluate the effectiveness of vitamin D replacement therapy on pain, electrophysiological parameters, ultrasonographic measurement results and functional status scales in CTS patients with low serum vitamin D levels. Materials and Methods: Our study was planned as an observational and analytical prospective. Vitamin D loading therapy was given to patients with serum vitamin D levels below 20ng/ml and mild-moderate CTS detected by electroneuromyography (ENMG). Patients with vitamin D levels above 20 ng/ml after 8 weeks were included in the study. Each patient was given a rest splint and exercise program. Patients were evaluated before and 3 months after treatment with electrophysiological, ultrasonographic, VAS, pinch-grip strength, two-point discrimination, monofilament test and Boston symptom severity scale.

Conditions

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Carpal Tunnel Syndrome Vitamin D Deficiency

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Vitamin D in Carpal Tunnel Syndrome

Group Type EXPERIMENTAL

Vitamin D

Intervention Type DRUG

Vitamin D replacement therapy was administered at 50,000 IU weekly for 8 weeks.

Interventions

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Vitamin D

Vitamin D replacement therapy was administered at 50,000 IU weekly for 8 weeks.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 18-70 years old male or female gender
* Those with mild to moderate CTS according to ENMG,
* Vitamin D level \<20.

Exclusion Criteria

* Severe CTS according to ENMG
* Thenar region atrophy
* diabetes mellitus,
* rheumatoid arthritis,
* hyperthyroidism,
* hypothyroidism
* Traumatic nerve injury, history of surgery
* Polyneuropathy
* Pregnancy
* Severe psychiatric illness
* Poor orientation and cooperation,
* Injection (corticosteroid, ozone, stem cell…) applied for CTS treatment within 3 months

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No