The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial

NCT ID: NCT06276777

Last Updated: 2024-02-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-01

Study Completion Date

2024-12-01

Brief Summary

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The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal hypersensitivity in adult patients for six months follow-up. patients will be asked to report pain degree on the visual analogue scale (VAS) along the follow up periods on both groups.

Detailed Description

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Conditions

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Dentin Hypersensitivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
Participants and both assessors will be blind to the type of material used.

Study Groups

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Varnish contains S-PRG (PRG Barrier Coat from Shofu)

Treatment of dentin hypersensitivity by application of tooth varnish containing S-PRG.

Group Type EXPERIMENTAL

Tooth varnish (PRG Barrier Coat from Shofu)

Intervention Type PROCEDURE

Treatment of cervical dentin hypersensitivity with tooth desensitizers.

Varnish contains sodium fluoride and functionalized tri-calcium phosphate(Clinpro white varnish 3M)

Treatment of dentin hypersensitivity by application of tooth varnish containing sodium fluoride with functionalized tri-calcium phosphate.

Group Type ACTIVE_COMPARATOR

Tooth varnish (Clinpro white varnish 3M)

Intervention Type PROCEDURE

Treatment of cervical dentin hypersensitivity with tooth desensitizers.

Interventions

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Tooth varnish (PRG Barrier Coat from Shofu)

Treatment of cervical dentin hypersensitivity with tooth desensitizers.

Intervention Type PROCEDURE

Tooth varnish (Clinpro white varnish 3M)

Treatment of cervical dentin hypersensitivity with tooth desensitizers.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Good oral hygiene.
* Cooperative patients who show interest to participate in the study and welling to sign the informed consent.
* Healthy patients with no history of previous systematic diseases that can affect their oral health.
* Normal and healthy gingival tissue.
* Teeth that have no cavitation or restorations.
* Patients with at least 20 natural permanent teeth and at least two teeth with a VAS score from 4 to 10.
* Anterior teeth.

Exclusion Criteria

* Allergic to the ingredients used in the study.
* Gastrointestinal disorders (They have repeated vomiting attacks).
* Medically compromised (They cannot tolerate the procedures).
* Taking desensitizing treatment in the last 6 months (It affects the outcome).
* Taking anti-inflammatory drugs (It affects the hypersensitivity perception).
* Pregnant females (They complain from nausea and repeated vomiting attacks)
* Smokers (Smoking will affect the oral hygiene and periodontal health).
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Eman Omar Elfarouk

OTHER

Sponsor Role lead

Responsible Party

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Eman Omar Elfarouk

masters degree student

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Eman Omar, bachelor

Role: PRINCIPAL_INVESTIGATOR

Cairo University faculty of oral and dental medicine

Locations

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Faculty of Dentistry Cairo University

Cairo, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Eman Omar El-farouk, masters

Role: CONTACT

01156677558

Facility Contacts

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Eman Omar, bachelor

Role: primary

01156677558

Other Identifiers

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SPRG Dentin Hypersensitivity

Identifier Type: -

Identifier Source: org_study_id

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