Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI Jakarta

NCT ID: NCT06268509

Last Updated: 2024-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

245 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-01

Study Completion Date

2024-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this MONAS Study is to learn about comprehensive monitoring and nutritional intervention among pregnant women in order to improve maternal and neonatal outcomes. The main questions it aims to answer are:

1. Are comprehensive monitoring and nutritional intervention among pregnant women can improve maternal outcomes (maternal death, preterm labour, preeclampsia, intrauterine infection, and bleeding during pregnancy and delivery) compared to standard maternal health services?
2. Are comprehensive monitoring and nutritional intervention among pregnant women can improve neonatal outcomes (neonatal death, low birth weight, intrauterine growth restriction, and neonatal asphyxia) compared to standard maternal health services?

Participants in the intervention group will receive:

* Fetomaternal ultrasound examination each trimester
* Complete laboratory examination for nutritional panel (complete blood count with reticulocyte profile and iron profile, vitamin D level, zinc level, fatty acid profile, electrophoresis for Thalassemia) as an addition to standard maternal routine laboratory examination
* Supplements: multivitamin, minerals, vitamin D, fatty acid
* Intervention regarding any abnormal results of nutritional panel
* All standard maternal health services according to Indonesian Ministry of Health protocol

Participants in the control group will receive:

\- All standard maternal health services according to Indonesian Ministry of Health protocol

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pregnancy Complications Maternal Death Preeclampsia Intrauterine Infection Pregnancy Hemorrhage Preterm Birth Neonatal Death Low; Birthweight, Extremely (999 Grams or Less) Asphyxia Neonatorum IUGR

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Intervention group

Participants in the intervention group will receive:

* Fetomaternal ultrasound examination each trimester by fetomaternal consultants
* Complete laboratory examination for nutritional panel (complete blood count with reticulocyte profile and iron profile, vitamin D level, zinc level, fatty acid profile, electrophoresis for Thalassemia) as an addition to standard maternal routine laboratory examination
* Supplements: multivitamin, minerals, vitamin D, fatty acid
* Intervention regarding any abnormal results of nutritional panel
* All standard maternal health services according to Indonesian Ministry of Health protocol

Group Type EXPERIMENTAL

Nutritional panel laboratory examination

Intervention Type DIAGNOSTIC_TEST

As stated in group description

Pregnancy supplements (other than provided by Ministry of Health)

Intervention Type DIETARY_SUPPLEMENT

As stated in group description

Fetomaternal ultrasound

Intervention Type DIAGNOSTIC_TEST

As stated in group description

Control group

Participants in the control group will receive:

\- All standard maternal health services according to Indonesian Ministry of Health protocol

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Nutritional panel laboratory examination

As stated in group description

Intervention Type DIAGNOSTIC_TEST

Pregnancy supplements (other than provided by Ministry of Health)

As stated in group description

Intervention Type DIETARY_SUPPLEMENT

Fetomaternal ultrasound

As stated in group description

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Pregnancy in 1st trimester
* Gestational age less than 10 weeks
* Living in Jakarta greater area
* Agree to participate

Exclusion Criteria

* Assisted reproductive technology (IVF)
* History of polycystic ovary syndrome
* History of chronic hypertension
* History of diabetes mellitus
* History of preeclampsia in the previous pregnancy
* Had chronic disease: heart disease, autoimmune disease, malignancy, chronic lung disease
* Planning to have delivery outside Jakarta greater area
* Poor obstetric history (miscarriage/ abortion more than 3 times)
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Dinas Kesehatan DKI Jakarta

UNKNOWN

Sponsor Role collaborator

Fakultas Kedokteran Universitas Indonesia

OTHER

Sponsor Role collaborator

Dr Cipto Mangunkusumo General Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Hardya Gustada Hikmahrachim

Principal Investigator, Member of Department of Child Health

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Rinawati Rohsiswatmo, Prof., M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Dr Cipto Mangunkusumo Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Jakarta Primary Care Health Facility (Puskesmas) under Jakarta Health Office

Jakarta, , Indonesia

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Indonesia

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Hardya G Hikmahrachim, M.D., M.Sc

Role: CONTACT

+6281386696655

Yurika E Susanti, M.D.

Role: CONTACT

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Risal, M.D., M.Sc.

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

MONAS

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Antioxidant Supplementation in Pregnant Women
NCT01232205 COMPLETED PHASE2/PHASE3