Comparison of the Efficacy of Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-24

Study Completion Date

2025-06-24

Brief Summary

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There are different neurolysis methods. Aim of this study is to compare two different methods, phenol block and corticosteroid local anesthetic block.

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Detailed Description

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Knee osteoarthritis is one of most frequent reason of knee pain. There are different treatment methods such as analgesic drug treatment, physical therapy techniques, intraarticular injections and neurolysis techniques. In this study, we will compare neurolysis techniques these are phenol block and corticosteroid local anesthetic block.

Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Phenol block group

Group Type EXPERIMENTAL

Phenol

Intervention Type DRUG

Chemical neurolysis

Corticosteroid and local anesthetic

Group Type ACTIVE_COMPARATOR

Celestone

Intervention Type DRUG

Chemical neurolysis with corticosteroid

Lidocain

Intervention Type DRUG

Chemical neurolysis with local anesthetic

Interventions

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Phenol

Chemical neurolysis

Intervention Type DRUG

Celestone

Chemical neurolysis with corticosteroid

Intervention Type DRUG

Lidocain

Chemical neurolysis with local anesthetic

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with knee osteoarthritis must have pain at least 6 months
* NRS score of knee pain equal or more than 5
* At least grade 3 in Kellgren-Lawrence grading scale
* Non responsive to life style change, weight control, exercises program, medical treatment and the other conservative treatments (physical therapy, intraarticular injections)
* Decreasing at NRS score more than %50 after diagnostic block
* Those who accept the consent form

Exclusion Criteria

* Patients who have acute knee injury
* Surgery history in knee
* Connective tissue disease that affect knee
* Sciatica
* Injection story in last 3 months
* Psychiatric or neurologic diseases that affect study
* Septic arthritis, active local or systemic infection
* Coagulopathy
* Pregnancy
* Allergic reaction

Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No