Data Collection in Lutetium Treated Prostate Cancer: Recording of Progression and Tumor Characteristics

NCT ID: NCT06260410

Last Updated: 2024-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-20

Study Completion Date

2027-02-01

Brief Summary

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This prospective study aims to collect data and blood biomarkers from patients undergoing Lu-PSMA therapy at the Erasmus MC. In doing so, it will provide real-world efficacy and safety data on the drug, gather dosimetry data and explore putative biomarkers to identify patients who most benefit from Lu-PSMA treatment.

Detailed Description

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Conditions

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Prostate Cancer Metastatic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Blood draw for ctDNA and circulating tumor cell collection.

During routine blood sample collection, additional blood will be drawn for analysis of ctDNA and to collect Circulating Tumor Cells.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Participants should be at least 18 years old.
* Participants should be able to understand the written information and be able to provide informed consent.
* Participants are planned to start treatment with Lu-PSMA as a part of regular clinical care.

Exclusion Criteria

None applicable
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Erasmus Medical Center

OTHER

Sponsor Role lead

Responsible Party

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S. L. W. (Stijn) Koolen

Assistant Professor, Hospital Pharmacist, Clinical Pharmacologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Erasmus MC

Rotterdam, South Holland, Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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Stijn Koolen, PhD

Role: CONTACT

+31638740656

Facility Contacts

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Stijn Koolen, PhD

Role: primary

+31638740656

Other Identifiers

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NL84672.078.23

Identifier Type: OTHER

Identifier Source: secondary_id

10512

Identifier Type: -

Identifier Source: org_study_id

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