Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

NCT ID: NCT06243588

Last Updated: 2025-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-25

Study Completion Date

2025-12-31

Brief Summary

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assess whether there is a correlation between some factors (age, sex, tumor volume, tumor site, chemotherapy-induced necrosis, radiation and biomarkers) and overall survival (OS) and relapse-free survival (RFS) in patients with Ewing sarcoma.

Identification of reliable prognostic factors could help to identify high-risk patients, which may require a different treatment and follow up.

Detailed Description

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Conditions

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Ewing Sarcoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients

patients treated at Rizzoli Institute from 1991 to 2021.

clinical records review

Intervention Type OTHER

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Interventions

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clinical records review

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Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male and female patients treated at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2021
* Age ≥ 2 years
* Diagnosis of Ewing Sarcoma
* Patients with available clinical and imaging data

Exclusion Criteria

* At least one inclusion criterion not met
Minimum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Ortopedico Rizzoli

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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IRCCS Itituto Ortopedico Rizzoli

Bologna, BO, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Costantino Errani

Role: CONTACT

0516366 ext. 103

Facility Contacts

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Costantino Errani, MD

Role: primary

References

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Grunewald TGP, Cidre-Aranaz F, Surdez D, Tomazou EM, de Alava E, Kovar H, Sorensen PH, Delattre O, Dirksen U. Ewing sarcoma. Nat Rev Dis Primers. 2018 Jul 5;4(1):5. doi: 10.1038/s41572-018-0003-x.

Reference Type RESULT
PMID: 29977059 (View on PubMed)

Pressman BD, Tourje EJ, Thompson JR. An early CT sign of ischemic infarction: increased density in a cerebral artery. AJR Am J Roentgenol. 1987 Sep;149(3):583-6. doi: 10.2214/ajr.149.3.583.

Reference Type RESULT
PMID: 3497548 (View on PubMed)

Other Identifiers

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ProEwing

Identifier Type: -

Identifier Source: org_study_id

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