Effects of Aerobic Exercise and Core Muscle Strengthening on Pain, Menstrual Pattern and QOL in Endometriosis

NCT ID: NCT06241040

Last Updated: 2024-04-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-03-15
• Study Completion Date: 2024-03-15

Brief Summary

Endometriosis is a complex and debilitating gynecological condition affecting millions of women worldwide. It is characterized by the abnormal growth of endometrial-like tissue outside the uterus, leading to chronic pelvic pain, dysmenorrhea, dyspareunia, and reduced quality of life. While pharmacological interventions are commonly prescribed to manage symptoms, their efficacy may be limited, and they often come with adverse effects. Therefore, exploring non-pharmacological approaches, such as exercise, is crucial in improving the management of endometriosis-related symptoms. Aerobic exercise has gained attention as a potential therapeutic intervention for endometriosis due to its positive effects on pain modulation, hormonal regulation, and overall well-being.

Detailed Description

This randomized controlled trial (RCT) will be conducted at Jinnah Hospital in Lahore, Pakistan, to investigate the effects of aerobic exercise with and without core muscle strengthening on pain, menstrual pattern, and quality of life in women diagnosed with endometriosis. The study will employ a convenient randomization sampling technique, aiming to recruit approximately 30 participants who meet the inclusion criteria. Eligible participants will be reproductive-age women experiencing endometriosis-related pain, with regular menstrual cycles or irregularities associated with endometriosis. They should be medically stable, cleared for physical activity, and willing to participate in an exercise intervention program. Exclusion criteria include pregnancy, severe endometriosis-related complications, significant comorbidities, recent surgery, ongoing hormonal treatments targeting endometriosis, inability to participate in exercise programs, and severe mental health conditions. By investigating these interventions, the study seeks to improve symptom management, menstrual regularity, and overall quality of life for women with endometriosis while considering safety and feasibility within the study setting.

Keywords: Endometriosis, Menstrual pattern, Aerobic Exercise, Core Muscle Strengthening, Quality of Life

Conditions

Endometriosis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Aerobic Exercise Group with Core Muscle strengthening Group

Participants assigned to this group will undergo a combination of aerobic exercise and core muscle strengthening interventions. The aerobic exercise component will be similar to the first group, while additional exercises targeting the core muscles (abdomen, back, and pelvis) will be included.

Group Type: EXPERIMENTAL

Aerobic Exercises with core Muscle strengthening

Intervention Type: OTHER

Participants assigned to this group will undergo a combination of aerobic exercise and core muscle strengthening interventions. The aerobic exercise component will be similar to the first group, while additional exercises targeting the core muscles (abdomen, back, and pelvis) will be included.

Aerobic Exercise without Core Muscle Strengthening Group

Participants assigned to this group will engage in aerobic exercise interventions

Group Type: ACTIVE_COMPARATOR

Aerobic Exercise without Core Muscle Strengthening

Intervention Type: OTHER

Aerobic Exercise without Core Muscle Strengthening

Interventions

Aerobic Exercises with core Muscle strengthening

Participants assigned to this group will undergo a combination of aerobic exercise and core muscle strengthening interventions. The aerobic exercise component will be similar to the first group, while additional exercises targeting the core muscles (abdomen, back, and pelvis) will be included.

Intervention Type: OTHER

Aerobic Exercise without Core Muscle Strengthening

Aerobic Exercise without Core Muscle Strengthening

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Women diagnosed with endometriosis.(16)
• Age range (e.g., 18-49 years)
• Regular menstrual cycles or menstrual irregularities associated with endometriosis.
• Medically stable and cleared for participation in physical activity.
• No contraindications for aerobic exercise or core muscle strengthening

Exclusion Criteria

• Pregnant individuals or those actively trying to conceive.
• Recent endometriosis-related surgeries/procedures
• Use of hormonal therapies/medications targeting endometriosis
• Severe endometriosis complications requiring immediate medical intervention
• Inability to engage in aerobic exercise.
• Significant cardiovascular/respiratory conditions
• Concurrent participation in another exercise/rehabilitation program

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 49 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Faiza Taufiq, PPDPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University, Senior Lecturer

Locations

Jinnah Hospital

Lahore, Punjab Province, Pakistan

Countries

Pakistan

Other Identifiers

S22C14G92019

Identifier Type: -

Identifier Source: org_study_id