Surgery and Exercise Versus Exercise Only for Chronic Patellofemoral Pain Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-12

Study Completion Date

2025-10-01

Brief Summary

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The goal of this randomised controlled trial is to compare a tuberositas transposition (TTT) surgery with a home exercise program (HEP) in patients with patellofemoral pain syndrome (PFPS). The study aims to evaluate the efficiency of TTT in conjunction with a HEP compared to a HEP alone in patients with chronic PFPS.

Participants will randomly be allocated to the surgery or HEP group. Researchers will compare the surgery and HEP groups to see if activity-related pain and patient reported outcome measures (PROMs) are different.

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Detailed Description

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Conditions

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Patellofemoral Pain Syndrome Tibial Tubercle Transfer Home Exercise Program

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Tibial Tubercle Transfer surgery

Tibial Tubercle Transfer surgery followed by a home exercise program.

Group Type EXPERIMENTAL

Tibial Tubercle Transfer

Intervention Type PROCEDURE

Patients will receive the TTT surgery followed by a home exercise program.

Home Exercise Program

A home exercise program.

Group Type ACTIVE_COMPARATOR

Home Exercise Program

Intervention Type PROCEDURE

Patients will receive an extensive home exercise program.

Interventions

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Tibial Tubercle Transfer

Patients will receive the TTT surgery followed by a home exercise program.

Intervention Type PROCEDURE

Home Exercise Program

Patients will receive an extensive home exercise program.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Characteristic history of PFPS (patellofemoral pain during knee loading physical activity, such as jumping, running, squatting);
* Symptoms lasting at least 12 months;
* Tibial tubercle trochlear groove (TT-TG) distance of 15mm or more on CT or MRI;
* Patellofemoral pain during daily life activities, such as: standing for an extended period, walking, or walking upstairs or downstairs

Exclusion Criteria

* Previous knee surgery;
* Reported knee ligamentous or meniscal injuries;

* Disabling general illness;
* A history of patellar dislocation; however, subjects with patellar subluxation are included in the study;
* Other knee problems than PFPS diagnosed clinically (such as jumper's knee);
* Other knee problems than PFPS diagnosed radiographically (such as osteochondritis - dissecans);
* Patients who cannot undergo surgery;
* Pregnancy;
* Patients with inability to complete follow-up or with limited understanding of the Dutch language

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes