Metastatic or Refractory Soft Tissue Sarcomas and Metronomic Cyclophosphamide: Further Assessment of Efficacy and Safety

NCT ID: NCT06216990

Last Updated: 2024-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-01-01

Study Completion Date

2022-07-01

Brief Summary

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Metronomic Cyclophosphamide's use in monotherapy as a palliative treatment against non-resectable and metastatic Soft Tissue Sarcomas relies on small retrospective cohorts' data.

Current litterature needs external validation of its efficacy and safety profile in these settings of usually frail patients.

The investigators assessed further data and aimed to identify predictive factors of metronomic cyclophosphamide impact in metastatic Soft Tissue Sarcomas.

Detailed Description

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Conditions

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Sarcoma Soft Tissue Sarcoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients over 18
* with inoperable or metastatic Soft Tissue Sarcoma
* treated with Metronomic Cyclophosphamide
* in 3 cancer care institutions located in 2 French regions (Bourgogne and Franche-Comté)
* between January 2005 and December 2021

Exclusion Criteria

* patients with bone, chondral sarcomas, desmoid, or gastrointestinal stromal tumors
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Besancon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clément BOLOGNINI

Role: PRINCIPAL_INVESTIGATOR

CHU Besançon

Other Identifiers

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2022/704

Identifier Type: -

Identifier Source: org_study_id

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