Pragmatic Clinical Trial of Two Recommendations Regarding Alcohol Consumption: a Pilot Study NAMETI_ALCOHOL

NCT ID: NCT06214416

Last Updated: 2024-01-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-01

Study Completion Date

2023-12-31

Brief Summary

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NAMETI-Alcohol, from the acronym for Navarra Medical Trialist Initiative, is a pilot study in which two patterns of alcohol consumption, abstention and Mediterranean alcohol-drinking pattern, and their effects on health in the short and medium term will be compared.

Detailed Description

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Background: Alcohol is the most consumed psychoactive substance in Spain. In 2016 it was the seventh leading risk factor for death and disability-adjusted lost years worldwide, and the first one in people between 15 and 49 years old.In the scientific community there is some controversy about what would be the best approach to face this great problem. On the one hand, there is evidence to recommend that there is no safe level of alcohol. However, on the other hand, there are studies that demonstrate the protective role of a moderate alcohol consumption. In this pilot study both options will be compared.

Methods: It is intended to recruit a total of 100 participants, including two observational cohorts of abstainers and drinkers. The intervention will be carried out in drinkers willing to change their alcohol consumption, divided into 2 groups of 50 participants, the abstention group and the Mediterranean alcohol-drinking pattern group. The Mediterranean alcohol-drinking pattern includes 5 aspects: moderate alcohol consumption (maximum of 1 drinks/day for women and 2 drinks/day for men), spread consumption throughout the week, drink with meals and never with an empty stomach, prefer wine and mainly red wine, as well as completely avoid episodes of binge-drinking. The main objective will be to compare the short and medium term effects on health of both patterns.

Conditions

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Alcohol Drinking

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

It is intended to recruit a total of 100 participants, including two observational cohorts of abstainers and drinkers. The intervention will be carried out in drinkers willing to change their alcohol consumption, divided into 2 groups of 150 participants, the abstention group and the Mediterranean alcohol-drinking pattern group.
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Abstention

These participants will be encouraged to totally avoid alcohol consumption.

Group Type ACTIVE_COMPARATOR

Abstention

Intervention Type BEHAVIORAL

All the intervention will be carried out online once a month for a year, focusing on nutritional, behavioral and scientific evidence aspects, that promote abstention.

Mediterranean alcohol-drinking pattern

These participants will be encouraged to change their pattern of consumption to a more Mediterranean way, which includes 5 aspects: moderate alcohol consumption (maximum of 2 drinks/day for women and 4 drinks/day for men), spread consumption throughout the week, drink with meals and never with an empty stomach, prefer wine and mainly red wine, as well as completely avoid episodes of binge-drinking.

Group Type ACTIVE_COMPARATOR

Mediterranean alcohol-drinking pattern

Intervention Type BEHAVIORAL

All the intervention will be carried out online once a month for a year, focusing on nutritional, behavioral and scientific evidence aspects, that promote the Mediterranean alcohol-drinking pattern.

Control of abstainers

This group will include all participants who consume less than 3 alcohol drinks a week at the time of recruitment.

Group Type NO_INTERVENTION

No interventions assigned to this group

Control of drinkers

This group will include all participants who don't want to change their alcohol-drinking pattern.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Abstention

All the intervention will be carried out online once a month for a year, focusing on nutritional, behavioral and scientific evidence aspects, that promote abstention.

Intervention Type BEHAVIORAL

Mediterranean alcohol-drinking pattern

All the intervention will be carried out online once a month for a year, focusing on nutritional, behavioral and scientific evidence aspects, that promote the Mediterranean alcohol-drinking pattern.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Consuming more than 3 drinks a week (except for the abstention-control arm)

Exclusion Criteria

* Sever chronic disease (cancer, cardiovascular disease, chronic hepatitis and mental illness)
* Pregnant women or breastfeeding
* Family or personal history of addiction, alcoholism or alcohol abuse
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ministry of Health, Spain

OTHER_GOV

Sponsor Role collaborator

Clinica Universidad de Navarra, Universidad de Navarra

OTHER

Sponsor Role lead

Responsible Party

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Maira Bes Rastrollo

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Navarra

Pamplona, Navarre, Spain

Site Status

Countries

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Spain

Other Identifiers

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NAMETI_ALCOHOL_10_2020

Identifier Type: -

Identifier Source: org_study_id

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