Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery
NCT ID: NCT06206330
Last Updated: 2024-01-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
140 participants
INTERVENTIONAL
2021-11-01
2022-11-01
Brief Summary
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Detailed Description
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A total of 140 patients, male and female, diagnosed with pilonidal sinus disease in our hospital between November 2021 and November 2022 were included in the study. Patients with acute pilonidal sinus abscess were excluded from the study, but chronic PS(pilonidal sinus) patients who had previously undergone abscess drainage were included in the study.
Patients under 18 years of age, relapsed patients, anemic patients (Hg \< 10 mg/dl), thrombocytopenic patients (Plt˂10⁶/ml), patients with a history of radiotherapy-chemotherapy, patients with diabetes and patients using steroids were excluded from the study.
Randomization was performed using the PASS computer program, and according to this randomization, fistulotomy and curettage technique (n=70) was applied to one group and fistulotomy and curettage + PRP (n=70) was applied to the other group.
Demographic information, family history, smoking, presence of abscess drainage, post-drainage antibiotic use, comorbidities, BMI, symptom duration, phenol application, laser epilation, number of sinus pits, presence of secondary orifice, basal PLT(platelet) count, size of the defect after sinus excision, wound infection, hematoma, length of hospital stay, presence of recurrence, pain in the first postoperative week, and time to complete epithelialization were evaluated.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Platelet rich plasma group
In this group we applied Platelet rich plasma after the surgery. The surgery was fistulotomy and curettage.
Platelet rich plasma
After application of platelet rich plasma after surgery, the patients have examined for infection, hematoma, pain, recurrence and the time of epithelialization of the wound.
Control group
In this group, we did the surgery as fistulotomy and curettage but we did not apply a Platelet rich plasma.
No interventions assigned to this group
Interventions
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Platelet rich plasma
After application of platelet rich plasma after surgery, the patients have examined for infection, hematoma, pain, recurrence and the time of epithelialization of the wound.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Acute pilonidal abcess
* Recurrent disease
* Anemic patients (Hg \< 10 mg/dl)
* Thrombocytopenic patients (Plt˂10⁶/ml)
* Patients with a history of radiotherapy-chemotherapy
* Diabetes Mellitus
* Patients using steroids
18 Years
59 Years
ALL
Yes
Sponsors
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İsmail Oskay Kaya
OTHER_GOV
Responsible Party
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İsmail Oskay Kaya
proffesor
Locations
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Diskapi Yildirim Beyazit Education And Research Hospital
Ankara, Altındag, Turkey (Türkiye)
Countries
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Other Identifiers
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23.08.2021 118/01
Identifier Type: -
Identifier Source: org_study_id
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