Revealing Engagement Patterns Among Hepatic Encephalopathy Patients
NCT ID: NCT06201988
Last Updated: 2024-02-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
500 participants
OBSERVATIONAL
2025-01-31
2027-01-31
Brief Summary
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In essence, this trial aims to deepen understanding of the factors influencing participation in hepatic encephalopathy clinical trials. Elevating participation rates could expedite the development of innovative treatments for this challenging condition.
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Detailed Description
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Conditions
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Study Design
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CASE_CROSSOVER
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Aged ≥ 18 years old
* No prior treatment for hepatic encephalopathy
Exclusion Criteria
* Inability to provide written informed consent
* Women of childbearing potential without a negative pregnancy test; or women who are lactating.
18 Years
ALL
No
Sponsors
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Power Life Sciences Inc.
INDUSTRY
Responsible Party
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Principal Investigators
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Michael B Gill
Role: STUDY_DIRECTOR
Power Life Sciences Inc.
Locations
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Power Life Sciences
San Francisco, California, United States
Countries
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Central Contacts
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Facility Contacts
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References
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Nardelli S, Gioia S, Faccioli J, Riggio O, Ridola L. Hepatic encephalopathy - recent advances in treatment and diagnosis. Expert Rev Gastroenterol Hepatol. 2023 Mar;17(3):225-235. doi: 10.1080/17474124.2023.2183386. Epub 2023 Feb 26.
Gairing SJ, Mangini C, Zarantonello L, Gioia S, Nielsen EJ, Danneberg S, Gabriel M, Ehrenbauer AF, Bloom PP, Ripoll C, Sultanik P, Galle PR, Labenz J, Thabut D, Zipprich A, Lok AS, Weissenborn K, Marquardt JU, Lauridsen MM, Nardelli S, Montagnese S, Labenz C. Prevalence of Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis: A Multicenter Study. Am J Gastroenterol. 2023 Dec 1;118(12):2191-2200. doi: 10.14309/ajg.0000000000002251. Epub 2023 Mar 20.
Bureau C, Thabut D, Jezequel C, Archambeaud I, D'Alteroche L, Dharancy S, Borentain P, Oberti F, Plessier A, De Ledinghen V, Ganne-Carrie N, Carbonell N, Rousseau V, Sommet A, Peron JM, Vinel JP. The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt : A Randomized Controlled Trial. Ann Intern Med. 2021 May;174(5):633-640. doi: 10.7326/M20-0202. Epub 2021 Feb 2.
Provided Documents
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Document Type: Informed Consent Form
Other Identifiers
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67278255
Identifier Type: -
Identifier Source: org_study_id
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