Patients Treated in Real Life With VEnetoclax for WAldenström Macroglobulinemia

NCT ID: NCT06200220

Last Updated: 2024-01-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-12-28

Study Completion Date

2025-12-01

Brief Summary

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Waldenström macroglobulinemia (WM) is an incurable disease. BCL2 antagonist, an important anti-apoptosys molecule, is already approved for the treatment of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia. Recently, a clinical trial including 32 patients with WM treated with Venetoclax showed an overall response rates of 84% and a major response rate of 81%. However, there is no in real life data, in the french population, of the efficiency of Venetoclax in WM. The aim of our multicentric retrospective study is to evaluate the efficiency and tolerance of Venetoclax in WM.

Detailed Description

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Conditions

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Waldenstrom's Macroglobulinaemia Refractory

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Venetoclax

Observational study

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Waldenstrom's macroglobulinemia
* Treatment with Venetoclax
* Non opposition
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Poitiers University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Poitiers

Poitiers, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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cécile tomowiak, Dr

Role: CONTACT

+33 (0)5.49.44.43.07

Mathilde Vonfeld, Intern

Role: CONTACT

+33 (0)5.49.44.43.07

Facility Contacts

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Xavier LELEU, Pr

Role: primary

+33(0)549444444

Other Identifiers

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WAVE

Identifier Type: -

Identifier Source: org_study_id

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