Yoga Training and Retinal Vasculature With Parkinson's Disease

NCT ID: NCT06194227

Last Updated: 2025-01-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-16

Study Completion Date

2024-12-30

Brief Summary

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This study will compare the impact of a novel high-speed, cued yoga program to a standard yoga program on retinal microvasculature, cognition and neuromuscular function in persons with Parkinson's disease.

Detailed Description

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Conditions

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Cognitive Change

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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High-speed, Cognitive Challenge Yoga

Participants in this group will receive high-speed yoga training for 24 consecutive weeks for a total of 72 training sessions.

Group Type EXPERIMENTAL

High-speed, Cognitive Challenge Yoga

Intervention Type BEHAVIORAL

Participants in this group will receive in-person high-speed yoga with cuing 3 times per week for 24 consecutive weeks for a total of 72 training sessions of 1 hour duration. Subjects will move as quickly as possible from one pose to another.

Traditional Yoga

Participants will perform standard Hatha yoga with slow controlled speed movements for 24 consecutive weeks for a total of 72 training sessions.

Group Type ACTIVE_COMPARATOR

Traditional Yoga

Intervention Type BEHAVIORAL

Participants will perform in-person controlled speed Hatha yoga 3 times per week for 24 weeks for a total of 72 sessions of 1 hour duration.

Interventions

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High-speed, Cognitive Challenge Yoga

Participants in this group will receive in-person high-speed yoga with cuing 3 times per week for 24 consecutive weeks for a total of 72 training sessions of 1 hour duration. Subjects will move as quickly as possible from one pose to another.

Intervention Type BEHAVIORAL

Traditional Yoga

Participants will perform in-person controlled speed Hatha yoga 3 times per week for 24 weeks for a total of 72 sessions of 1 hour duration.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Parkinson's disease (H\&Y 1, 2, and 3) confirmed by pretest administration of the UPDRS,
2. 55-90 years of age,
3. Montreal Cognitive Assessment \> 17.

Exclusion Criteria

1. Uncontrolled cardiovascular or neuromuscular diseases that prevent participation in a training program;
2. cerebrovascular disease;
3. documented HIV infection or other immunodeficiency syndrome;
4. any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus, or other serious concomitant medical illness;
5. a history of ocular surgeries (except for cataract surgery more than 6 months ago) or other ocular diseases;
6. bilateral moderate or severe cataracts;
7. refractive errors of myopia, hyperopia and/or astigmatism more than 6.0 Diopters.
Minimum Eligible Age

50 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Joseph Signorile

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Joseph F. Signorile, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami

Coral Gables, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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20231203

Identifier Type: -

Identifier Source: org_study_id

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