Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection

NCT ID: NCT06189183

Last Updated: 2024-02-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-11

Study Completion Date

2040-12-31

Brief Summary

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The purpose of this study is to evaluate the efficiency and toxicity of adjuvant hypofractionation radiotherapy for thymic epithelial tumours after complete resection.

Detailed Description

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Adjuvant Radiotherapy(Postoperative radiotherapy) is proposed in stage II and III thymic carcinoma,stage III thymoma,stage IIB B2/B3 thymomas.

Hypofractionation Radiotherapy is used in this study. The purpose of this study is to evaluate the efficiency and toxicity of adjuvant hypofractionation radiotherapy for thymic epithelial tumours after complete resection.

Conditions

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Thymus Neoplasms

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Adjuvant Hypofractionation Radiotherapy

Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection

Group Type EXPERIMENTAL

Adjuvant Hypofractionation Radiotherapy

Intervention Type RADIATION

Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection

Interventions

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Adjuvant Hypofractionation Radiotherapy

Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Thymoma and Thymic carcinoma confirmed by histology or cytology
* R0 resection (complete resection)
* stage II and III thymic carcinoma,stage III thymoma,stage IIB B2/B3 thymomas.
* Karnofsky performance status(KPS) 80, 90 or 100.
* Having sufficient Pulmonary function, renal function and liver function. Neutrophile granulocyte count\>1.5×109 /L, platelet count\>80×109 /L, hemoglobin ≥10g/dL.

Exclusion Criteria

* Prior thoracic radiotherapy.
* Uncontrolled Comorbidities.
* Pregnant or nursing mother.
* Pneumonia
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tao Zhang, Dr.

Role: PRINCIPAL_INVESTIGATOR

National Cancer Center/Cancer Hospital, CAMS

Locations

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National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Tao Zhang, Dr.

Role: CONTACT

8618911006677

Facility Contacts

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Tao Zhang, Dr.

Role: primary

8618911006677

Other Identifiers

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NCC4287

Identifier Type: -

Identifier Source: org_study_id

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