Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function

NCT ID: NCT06186713

Last Updated: 2024-01-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

4784 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-30

Study Completion Date

2023-08-01

Brief Summary

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Pulmonary hypertension (PH) has a negative effect on acute myocardial infarction (AMI) patients and appears to be closely associated with reduced left ventricular function. However, its impact on AMI patients with reduced left ventricular function remains unclear. This retrospective study included AMI patients with reduced left ventricular function to investigate the prognostic value of PH in this specific type of patient. Meanwhile, a nomogram would be established basing on the identified independent risk factors, hoping to provide a novel risk stratification for them.

Detailed Description

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Conditions

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Acute Myocardial Infarction Pulmonary Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Pulmonary hypertension (PH) group

The PH group comprised of patients with systolic pulmonary artery pressure (sPAP) ≥ 35mmHg measured by echocardiology.

This was an observational study, and no Intervention was given to the patients.

Intervention Type OTHER

This was an observational study, and no Intervention was given to the patients.

Control group

The control group included patients with systolic pulmonary artery pressure (sPAP) \<35mmHg measured by echocardiology.

This was an observational study, and no Intervention was given to the patients.

Intervention Type OTHER

This was an observational study, and no Intervention was given to the patients.

Interventions

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This was an observational study, and no Intervention was given to the patients.

This was an observational study, and no Intervention was given to the patients.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* The patients who were hospitalized for AMI with reduced left ventricular function at the First Affiliated Hospital of Jiaotong University from January 2018 to January 2022.

Exclusion Criteria

* Myocardial infarction complicated by cardiac rupture.
* Significant pre-existing heart failure.
* Other comorbidities such as malignancy that may significantly affect prognosis.
* Incomplete clinical data.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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First Affiliated Hospital Xi'an Jiaotong University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yang Yan

Role: PRINCIPAL_INVESTIGATOR

First Affiliated Hospital Xi'an Jiaotong University

Locations

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First Affiliated Hospital of Xian Jiaotong University

Xi'an, Shaanxi, China

Site Status

Countries

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China

References

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Liu Q, Zhao C, Dang P, Li Y, Yan Y. Prognostic value of pulmonary hypertension with a nomogram in acute myocardial infarction patients with reduced left ventricular function. Front Cardiovasc Med. 2024 Apr 22;11:1368139. doi: 10.3389/fcvm.2024.1368139. eCollection 2024.

Reference Type DERIVED
PMID: 38711791 (View on PubMed)

Other Identifiers

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XJTU1AF2023LSK-406

Identifier Type: -

Identifier Source: org_study_id

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