the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension

NCT ID: NCT02061787

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

4000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-09-30

Study Completion Date

2030-09-08

Brief Summary

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cardiopulmonary exercise test evaluate patients with pulmonary hypertension before and after medical or balloon pulmonary angioplasty treatment

Detailed Description

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patients diagnosed with pulmonary hypertension, including pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension, will be evaluated by cardio pulmonary exercise test before and after medical or balloon pulmonary angioplasty treatment

Conditions

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Pulmonary Hypertension Chronic Thromboembolic Pulmonary Hypertension Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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cardiopulmonary exercise testing

patients diagnosed with pulmonary hypertension, including pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension, were evaluated by cardiopulmonary exercise testing before and after medical or balloon pulmonary angioplasty treatment

balloon pulmonary angioplasty

Intervention Type DEVICE

patients with chronic thromboembolic pulmonary hypertension who underwent balloon pulmonary angioplasty

Interventions

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balloon pulmonary angioplasty

patients with chronic thromboembolic pulmonary hypertension who underwent balloon pulmonary angioplasty

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* pulmonary arterial hypertension;( WHO1)
* chronic thromboembolic pulmonary hypertension;
* pulmonary arterial hypertension due to other cause;

Exclusion Criteria

* massive hemoptysis;
* unable to accomplish cardiopulmonary exercise testing due to neuromuscular disorders;
* recent recurrent syncope;
* pulmonary hypertension due to hypoxia;
* pulmonary hypertension due to left heart diseases.
Minimum Eligible Age

5 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese Pulmonary Vascular Disease Research Group

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zhihong Liu, MD,PhD

Role: STUDY_DIRECTOR

Fuwai Hospital, National Center for Cardiovascular Diseases

Locations

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center of pulmonary vascular disease, Fuwai hospital

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Zhihong Liu, Doctor

Role: CONTACT

8601088396590

Facility Contacts

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Xiuping Ma

Role: primary

8601088396816

References

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Li X, Duan A, Jin Q, Zhang Y, Luo Q, Zhao Q, Yan L, Huang Z, Hu M, Xiong C, Zhao Z, Liu Z. Exercise feature and predictor of prognosis in patients with pulmonary artery stenosis-associated pulmonary hypertension. ESC Heart Fail. 2022 Dec;9(6):4198-4208. doi: 10.1002/ehf2.14154. Epub 2022 Sep 13.

Reference Type DERIVED
PMID: 36101502 (View on PubMed)

Tang Y, Yao L, Liu Z, Ma X, Luo Q, Zhao Z, Huang Z, Tu L, Gao L, Jin Q, Ni X, Xiong C. Effect of calcium channel blockers evaluated by cardiopulmonary exercise testing in idiopathic pulmonary arterial hypertension responding to acute pulmonary vasoreactivity testing. Pulm Pharmacol Ther. 2017 Apr;43:26-31. doi: 10.1016/j.pupt.2017.01.012. Epub 2017 Feb 1.

Reference Type DERIVED
PMID: 28159512 (View on PubMed)

Other Identifiers

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CPETPH

Identifier Type: -

Identifier Source: org_study_id

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