Prevalence of Peripheral Vascular Diseases and Presentation in Patients With Autoimmune Diseases

NCT ID: NCT06169865

Last Updated: 2023-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-10

Study Completion Date

2024-05-10

Brief Summary

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Rheumatic autoimmune diseases include conditions such as systemic lupus rheumatoid arthritis systemic sclerosis in which connective tissues are frequently targeted.

Autoimmune diseases as a group are among the leading causes of death and morbidity in the industrial world and pose an immense socioeconomic burden despite the considerable accumulative burden of these diseases only a small number of multinational registries for a few selected autoimmune diseases have been devised.

Numerous autoimmune inflammatory diseases have been associated with various forms of vasculopathy and increase vascular disease risk such as accelerated atherogenesis and thromboembolic events as digital and acral gangrene secondary Raynaud syndrome arterial aneurysm and different cutaneous ulcer.

The etiopathogenesis os increased risk of peripheral vascular diseases and presentation in autoimmune diseases is not entirely clear but multiple contibutors have been explored especially in the context of systemic inflammation and disordered thrombogenesis.

Detailed Description

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Conditions

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Peripheral Vascular Diseases and Presentation in Patient With Autoimmune Diseases

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Interventions

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cross sectional study

cross sectional study to explore magnitude of peripheral vascular diseases and presentations in patients with autoimmune diseases in sohag society.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* all ages
* Both sexes
* Recent or past history of vascular diseases or presentation in any proven autoimmune diseases according to the guidlines.

Exclusion Criteria

* patients refuse the study
* patients do not have established diagnosis of vascular diseases .
* patients not completely approved to have autoimmune diseases.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hossam Adly Mohamed

OTHER

Sponsor Role lead

Responsible Party

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Hossam Adly Mohamed

resident at vascular surgery department

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Sohag university Hospital

Sohag, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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hosam A Mohamed, resident

Role: CONTACT

Phone: 01023012244

Email: [email protected]

Ahmed s Abd Alfatah, assistant professor

Role: CONTACT

Phone: 01096495577

Facility Contacts

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Magdy M Amin, professor

Role: primary

References

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Cooper GS, Bynum ML, Somers EC. Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases. J Autoimmun. 2009 Nov-Dec;33(3-4):197-207. doi: 10.1016/j.jaut.2009.09.008. Epub 2009 Oct 9.

Reference Type BACKGROUND
PMID: 19819109 (View on PubMed)

Zoller B, Li X, Sundquist J, Sundquist K. Autoimmune diseases and venous thromboembolism: a review of the literature. Am J Cardiovasc Dis. 2012;2(3):171-83. Epub 2012 Jul 25.

Reference Type BACKGROUND
PMID: 22937487 (View on PubMed)

Bashal F. Thrombosis in Rheumatological Diseases. 2021 Jan 6. In: Almoallim H, Cheikh M, editors. Skills in Rheumatology [Internet]. Singapore: Springer; 2021. Chapter 12. Available from http://www.ncbi.nlm.nih.gov/books/NBK585742/

Reference Type BACKGROUND
PMID: 36315801 (View on PubMed)

Pyrpasopoulou A, Chatzimichailidou S, Aslanidis S. Vascular disease in systemic lupus erythematosus. Autoimmune Dis. 2012;2012:876456. doi: 10.1155/2012/876456. Epub 2012 Aug 22.

Reference Type BACKGROUND
PMID: 22957213 (View on PubMed)

Other Identifiers

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soh-Med-23-10-03MS

Identifier Type: -

Identifier Source: org_study_id