Effect of Intraoperative Music on Inflammatory Response in Donor Hepatectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

61 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-22

Study Completion Date

2024-09-09

Brief Summary

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It has been reported that non-pharmacological methods can be used as an alternative in addition to pharmacological methods to reduce pain, anxiety, stress and inflammatory response that begins with the surgical incision in the intraoperative period and continues throughout the operation. It has been reported that music can be used as an alternative non-pharmacological method to reduce pain and anxiety in the perioperative period, as well as surgical stress and the related stress response.

The aim of this study is to test the hypothesis that music used as a non-pharmacological method in the intraoperative period can reduce inflammatory response in living donor hepatectomy.

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Detailed Description

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Conditions

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Transplantation Hepatectomy Music Stress Response

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Music Group

Music will be delivered via headphones intraoperatively. Blood samples will be collected as per the protocol.

Group Type ACTIVE_COMPARATOR

music

Intervention Type OTHER

A music with a standard volume will be delivered to the patients via headphones from the beginning of anesthesia induction to extubation.

Control Group

Headphones will be applied but no music will be played intraoperatively. Blood samples will be collected as per the protocol.

Group Type ACTIVE_COMPARATOR

no music

Intervention Type OTHER

Headphones will be applied to the patients but no music will be played from the beginning of anesthesia induction to extubation.

Interventions

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music

A music with a standard volume will be delivered to the patients via headphones from the beginning of anesthesia induction to extubation.

Intervention Type OTHER

no music

Headphones will be applied to the patients but no music will be played from the beginning of anesthesia induction to extubation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing donor hepatectomy
* American Society of Anesthesiologists class 1 to 2
* Ability to consent

Exclusion Criteria

* American Society of Anesthesiologists greater than 2
* Documented or known sensitivity to any drug to be used in the study.
* Patient with immunosuppressant/ cytotoxic/ steroid therapy.
* not understand the aim and objectives of the study

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No