A Novel Multisensory-Rhythmic Intervention in Geriatric Rehabilitation

NCT ID: NCT06151626

Last Updated: 2025-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-05

Study Completion Date

2026-12-31

Brief Summary

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Human performance takes shape from the dynamic interaction between person, environment, and task. Goal-directed action is a complex task, which requires the elderly to adapt their motor response according to the environment constraints and task requirements to accomplish the task goal. Among age-related problems, motor control deficits are often the main problems which restricts the frail elderly from maintaining independence for activities of daily living. Therefore, to preserve the quality of life, motor function of the elderly must be taken into consideration, including early detection of motor control problems and development of appropriate intervention strategy for persons with either healthy or pathological brain aging. Rhythmic skill training which is a new mode of dual tasks using rhythmic cueing as an external agent for facilitating an automatized motor task. During training, rhythmic skill training can provide multi-component of sensory stimulation, strengthen motor planning and optimize motor execution, therefore, it will improve the motor performance for the elderly or patients with mild cognitive impairment. In addition, the neuroplastic changes related to sensory processing, selective attention, or working memory demands through music rhythm training can facilitate the cognitive function for the elderly which is a current trend of geriatric rehabilitation. Moreover, the advantage of virtual reality is that it provides important information related to knowledge of result, which can induce better motor and cognitive training effects. Therefore, this research project will focus on assessing and intervening motor adaptation of upper extremity for the healthy elderly and patients with mild cognitive impairment. The first purpose of the project will analyze the difference in efficiency of responsive and predictive grasping motor adaptation among the healthy young adults, healthy elderly and patients with mild cognitive impairment through a test of perturbation-based of pinch-holding-up-activity, and use artificial intelligence for more accurate classification for the grasp pattern of healthy young adults, elderly and patients with mild cognitive impairment. The second one is to verify the effects of virtual-reality based rhythmic skill training system on the motor adaptation capability of upper limb and cognition for the elderly and patients with mild cognitive impairment.

Detailed Description

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Conditions

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Virtual Reality Hand Mirror Geriatric Kinesiology, Applied

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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virtual-reality based rhythmic skill training

Participants wear VR headsets and Oculus Touch controllers and undergo rhythm skill training for a total of 35 minutes.

Group Type EXPERIMENTAL

virtual-reality based rhythmic skill training

Intervention Type OTHER

Participants wear VR headsets and Oculus Touch controllers and undergo rhythm skill training for a total of 35 minutes.

breathing and muscle relaxation exercises

Intervention Type OTHER

5 minutes of breathing and muscle relaxation exercises

rhythmic skill training with visual feedback

The rhythm skill training activities in this group are the same as the virtual reality-based system. Participants received 35 minutes of rhythm skill training presented through a computer interface

Group Type ACTIVE_COMPARATOR

rhythmic skill training with visual feedback

Intervention Type OTHER

The rhythm skill training activities in this group are the same as the virtual reality-based system. Participants received 35 minutes of rhythm skill training presented through a computer interface

breathing and muscle relaxation exercises

Intervention Type OTHER

5 minutes of breathing and muscle relaxation exercises

strengthening group

The patients receive an upper limb strengthening exercise program under the supervision of a therapist to ensure that the strengthening exercises are performed correctly. This includes: proprioceptive neuromuscular facilitation, resistance training, and tendon gliding exercises.

Group Type ACTIVE_COMPARATOR

strengthening group

Intervention Type OTHER

Participants receive an upper limb strengthening exercise program under the supervision of a therapist to ensure that the strengthening exercises are performed correctly. This includes: proprioceptive neuromuscular facilitation, resistance training, and tendon gliding exercises.

breathing and muscle relaxation exercises

Intervention Type OTHER

5 minutes of breathing and muscle relaxation exercises

Interventions

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virtual-reality based rhythmic skill training

Participants wear VR headsets and Oculus Touch controllers and undergo rhythm skill training for a total of 35 minutes.

Intervention Type OTHER

rhythmic skill training with visual feedback

The rhythm skill training activities in this group are the same as the virtual reality-based system. Participants received 35 minutes of rhythm skill training presented through a computer interface

Intervention Type OTHER

strengthening group

Participants receive an upper limb strengthening exercise program under the supervision of a therapist to ensure that the strengthening exercises are performed correctly. This includes: proprioceptive neuromuscular facilitation, resistance training, and tendon gliding exercises.

Intervention Type OTHER

breathing and muscle relaxation exercises

5 minutes of breathing and muscle relaxation exercises

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Montreal Cognitive Assessment (MoCA) score of 23 or higher,
2. Clinical Dementia Rating (CDR) of 0 (for normal subjects) or 1 (for mild cognitive impairment subjects),
3. Healthy young participants aged between 20-39 years, healthy older adults and mild cognitive impairment participants aged between 65-85 years,
4. No skeletal, muscular, or neurological problems in the upper limbs in the past year, and
5. Sufficient visual acuity to complete the tasks.

Exclusion Criteria

* Any subjects with significant mental illness, central nervous system disorders, or medical history
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cheng-Kung University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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National Cheng-Kung University Hospital

Tainan City, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Hsiu-Yun Hsu, Ph.D

Role: CONTACT

886-6-2353535 ext. 2669

Facility Contacts

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Hsiu-Yun Hsu, PhD

Role: primary

Other Identifiers

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B-ER-111-482

Identifier Type: -

Identifier Source: org_study_id

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