Trial Outcomes & Findings for Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders (NCT NCT06134128)

Results Overview

Number of participants included from eligible Veterans; satisfactory recruitment defined as enrolment of ≥ 50% of eligible Veterans.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

19 participants

Primary outcome timeframe

From enrollment to the end of treatment at 8 weeks

Results posted on

2025-11-21

Participant Flow

Participant milestones

Participant milestones
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints. Motivationally Enhanced Compensatory Cognitive Training for Addictions Group: 8-week manualized group-based behavioral intervention delivered via telehealth
Overall Study STARTED	19
Overall Study COMPLETED	15
Overall Study NOT COMPLETED	4

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group n=19 Participants Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints.
Age, Continuous	49.9 years STANDARD_DEVIATION 14.0 • n=68 Participants
Sex: Female, Male Female	3 Participants n=68 Participants
Sex: Female, Male Male	16 Participants n=68 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=68 Participants
Race (NIH/OMB) Asian	0 Participants n=68 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=68 Participants
Race (NIH/OMB) Black or African American	0 Participants n=68 Participants
Race (NIH/OMB) White	19 Participants n=68 Participants
Race (NIH/OMB) More than one race	0 Participants n=68 Participants
Race (NIH/OMB) Unknown or Not Reported	0 Participants n=68 Participants
Education	13.9 years STANDARD_DEVIATION 2.8 • n=68 Participants

PRIMARY outcome

Timeframe: From enrollment to the end of treatment at 8 weeks

Population: Thirty-two individuals expressed interest, and 29 completed screening; 19 Veterans enrolled in the study.

Number of participants included from eligible Veterans; satisfactory recruitment defined as enrolment of ≥ 50% of eligible Veterans.

Outcome measures

Outcome measures
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group n=29 Participants Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints. Motivationally Enhanced Compensatory Cognitive Training for Addictions Group: 8-week manualized group-based behavioral intervention delivered via telehealth
Recruitment Rate	19 Participants

PRIMARY outcome

Timeframe: From enrollment to the end of treatment at 8 weeks

Satisfactory retention rate ≥ 75% of participants completing the intervention.

Outcome measures

Outcome measures
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group n=19 Participants Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints. Motivationally Enhanced Compensatory Cognitive Training for Addictions Group: 8-week manualized group-based behavioral intervention delivered via telehealth
Study Retention	15 Participants

PRIMARY outcome

Timeframe: From enrollment to the end of treatment at 8 weeks

% of participants where follow-up visit was completed.

Outcome measures

Outcome measures
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group n=19 Participants Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints. Motivationally Enhanced Compensatory Cognitive Training for Addictions Group: 8-week manualized group-based behavioral intervention delivered via telehealth
Feasibility of Testing Procedures	15 Participants

PRIMARY outcome

Timeframe: From enrollment to the end of treatment at 8 weeks

% of participants with complete data sets.

Outcome measures

Outcome measures
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group n=19 Participants Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints. Motivationally Enhanced Compensatory Cognitive Training for Addictions Group: 8-week manualized group-based behavioral intervention delivered via telehealth
Feasibility of Data Collection Methods	15 Participants

PRIMARY outcome

Timeframe: Measured after the 8-week intervention

Satisfactory acceptability ≥ 70% of participants score ≥ 24 on the Client Satisfaction Questionnaire (CSQ-8). CSQ-8 scores range from 8-32, with higher scores indicating greater satisfaction with the intervention.

Outcome measures

Outcome measures
Measure	Motivationally Enhanced Compensatory Cognitive Training for Addictions Group n=15 Participants Motivationally Enhanced Compensatory Cognitive Training for Addictions (ME-CCT-A) is a manualized group-based behavioral intervention (8 weeks, 2 hour per week) designed to improve cognitive functioning in Veterans with substance use disorders (SUDs) and cognitive complaints. Motivationally Enhanced Compensatory Cognitive Training for Addictions Group: 8-week manualized group-based behavioral intervention delivered via telehealth
Acceptability, by Participant Report	15 participants' score ≥ 24

Adverse Events

Motivationally Enhanced Compensatory Cognitive Training for Addictions Group

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kate Shirley, PhD

VA Portland Healthcare System

Phone: 503-220-8262

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place