Trial Outcomes & Findings for Lung Cancer Screening Eligibility Assessment (NCT NCT06133816)

NCT ID: NCT06133816

Last Updated: 2025-05-31

Results Overview

The proportion of participants that answers all three survey questions via text message among all those randomized.

Recruitment status

COMPLETED

Study phase

Target enrollment

6125 participants

Primary outcome timeframe

7 days

Results posted on

2025-05-31

Participant Flow

No significant events

Participant milestones

Participant milestones
Measure	Arm 1 (Introductory Message A + Tobacco Use Message A + Incentive) Participants will receive two framed messages (AA) plus an incentive Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 2 (Introductory Message A + Tobacco Use Message A) Participants will receive two framed messages (AA) Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 3 (Introductory Message A + Tobacco Use Message B + Incentive) Participants will receive two framed messages (AB) plus an incentive Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 4 (Introductory Message A + Tobacco Use Message B) Participants will receive two framed messages (AB) Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Arm 5 (Introductory Message B + Tobacco Use Message A + Incentive) Participants will receive two framed messages (BA) plus an incentive Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 6 (Introductory Message B + Tobacco Use Message A) Participants will receive two framed messages (BA) Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 7 (Introductory Message B + Tobacco Use Message B + Incentive) Participants will receive two framed messages (BB) plus an incentive Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 8 (Introductory Message B + Tobacco Use Message B) Participants will receive two framed messages (BB) Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Arm 9 (Introductory Message C + Tobacco Use Message A + Incentive) Participants will receive two framed messages (CA) plus an incentive Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 10 (Introductory Message C + Tobacco Use Message A) Participants will receive two framed message (CA) Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 11 (Introductory Message C + Tobacco Use Message B + Incentive) Participants will receive two framed messages (CB) plus an incentive Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 12 (Introductory Message C + Tobacco Use Message B) Participants will receive two framed messages (CB) Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).
Overall Study STARTED	509	509	515	509	510	510	512	509	511	511	509	511
Overall Study COMPLETED	509	509	515	509	510	510	512	509	511	511	509	511
Overall Study NOT COMPLETED	0	0	0	0	0	0	0	0	0	0	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Lung Cancer Screening Eligibility Assessment

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Arm 1 (Introductory Message A + Tobacco Use Message A + Incentive) n=509 Participants Participants will receive two framed messages (AA) plus an incentive Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 2 (Introductory Message A + Tobacco Use Message A) n=509 Participants Participants will receive two framed messages (AA) Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 3 (Introductory Message A + Tobacco Use Message B + Incentive) n=515 Participants Participants will receive two framed messages (AB) plus an incentive Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 4 (Introductory Message A + Tobacco Use Message B) n=509 Participants Participants will receive two framed messages (AB) Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Arm 5 (Introductory Message B + Tobacco Use Message A + Incentive) n=510 Participants Participants will receive two framed messages (BA) plus an incentive Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 6 (Introductory Message B + Tobacco Use Message A) n=510 Participants Participants will receive two framed messages (BA) Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 7 (Introductory Message B + Tobacco Use Message B + Incentive) n=512 Participants Participants will receive two framed messages (BB) plus an incentive Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 8 (Introductory Message B + Tobacco Use Message B) n=509 Participants Participants will receive two framed messages (BB) Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Arm 9 (Introductory Message C + Tobacco Use Message A + Incentive) n=511 Participants Participants will receive two framed messages (CA) plus an incentive Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 10 (Introductory Message C + Tobacco Use Message A) n=511 Participants Participants will receive two framed message (CA) Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 11 (Introductory Message C + Tobacco Use Message B + Incentive) n=509 Participants Participants will receive two framed messages (CB) plus an incentive Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 12 (Introductory Message C + Tobacco Use Message B) n=511 Participants Participants will receive two framed messages (CB) Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Total n=6125 Participants Total of all reporting groups
Age, Continuous	65.02 years STANDARD_DEVIATION 0.35 • n=5 Participants	64.33 years STANDARD_DEVIATION 0.33 • n=7 Participants	64.50 years STANDARD_DEVIATION 0.33 • n=5 Participants	64.48 years STANDARD_DEVIATION 0.34 • n=4 Participants	64.15 years STANDARD_DEVIATION 0.33 • n=21 Participants	64.67 years STANDARD_DEVIATION 0.34 • n=8 Participants	64.21 years STANDARD_DEVIATION 0.33 • n=8 Participants	63.33 years STANDARD_DEVIATION 0.35 • n=24 Participants	64.56 years STANDARD_DEVIATION 0.33 • n=42 Participants	64.28 years STANDARD_DEVIATION 0.36 • n=42 Participants	64.40 years STANDARD_DEVIATION 0.33 • n=42 Participants	63.89 years STANDARD_DEVIATION 0.32 • n=42 Participants	64.32 years STANDARD_DEVIATION 0.10 • n=36 Participants
Sex: Female, Male Female	259 Participants n=5 Participants	260 Participants n=7 Participants	261 Participants n=5 Participants	258 Participants n=4 Participants	259 Participants n=21 Participants	259 Participants n=8 Participants	261 Participants n=8 Participants	258 Participants n=24 Participants	260 Participants n=42 Participants	259 Participants n=42 Participants	258 Participants n=42 Participants	260 Participants n=42 Participants	3112 Participants n=36 Participants
Sex: Female, Male Male	250 Participants n=5 Participants	249 Participants n=7 Participants	254 Participants n=5 Participants	251 Participants n=4 Participants	251 Participants n=21 Participants	251 Participants n=8 Participants	251 Participants n=8 Participants	251 Participants n=24 Participants	251 Participants n=42 Participants	252 Participants n=42 Participants	251 Participants n=42 Participants	251 Participants n=42 Participants	3013 Participants n=36 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	7 Participants n=5 Participants	14 Participants n=7 Participants	15 Participants n=5 Participants	11 Participants n=4 Participants	16 Participants n=21 Participants	10 Participants n=8 Participants	8 Participants n=8 Participants	15 Participants n=24 Participants	16 Participants n=42 Participants	9 Participants n=42 Participants	9 Participants n=42 Participants	6 Participants n=42 Participants	136 Participants n=36 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants	0 Participants n=4 Participants	0 Participants n=21 Participants	0 Participants n=8 Participants	0 Participants n=8 Participants	0 Participants n=24 Participants	0 Participants n=42 Participants	0 Participants n=42 Participants	0 Participants n=42 Participants	0 Participants n=42 Participants	0 Participants n=36 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	502 Participants n=5 Participants	495 Participants n=7 Participants	500 Participants n=5 Participants	498 Participants n=4 Participants	494 Participants n=21 Participants	500 Participants n=8 Participants	504 Participants n=8 Participants	494 Participants n=24 Participants	495 Participants n=42 Participants	502 Participants n=42 Participants	500 Participants n=42 Participants	505 Participants n=42 Participants	5989 Participants n=36 Participants
Race (NIH/OMB) American Indian or Alaska Native	1 Participants n=5 Participants	1 Participants n=7 Participants	2 Participants n=5 Participants	0 Participants n=4 Participants	2 Participants n=21 Participants	2 Participants n=8 Participants	0 Participants n=8 Participants	1 Participants n=24 Participants	1 Participants n=42 Participants	4 Participants n=42 Participants	3 Participants n=42 Participants	4 Participants n=42 Participants	21 Participants n=36 Participants
Race (NIH/OMB) Asian	6 Participants n=5 Participants	6 Participants n=7 Participants	6 Participants n=5 Participants	12 Participants n=4 Participants	8 Participants n=21 Participants	8 Participants n=8 Participants	10 Participants n=8 Participants	8 Participants n=24 Participants	5 Participants n=42 Participants	7 Participants n=42 Participants	14 Participants n=42 Participants	7 Participants n=42 Participants	97 Participants n=36 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	1 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants	0 Participants n=4 Participants	1 Participants n=21 Participants	0 Participants n=8 Participants	0 Participants n=8 Participants	0 Participants n=24 Participants	1 Participants n=42 Participants	0 Participants n=42 Participants	0 Participants n=42 Participants	0 Participants n=42 Participants	3 Participants n=36 Participants
Race (NIH/OMB) Black or African American	94 Participants n=5 Participants	94 Participants n=7 Participants	95 Participants n=5 Participants	93 Participants n=4 Participants	95 Participants n=21 Participants	95 Participants n=8 Participants	95 Participants n=8 Participants	94 Participants n=24 Participants	94 Participants n=42 Participants	94 Participants n=42 Participants	94 Participants n=42 Participants	94 Participants n=42 Participants	1131 Participants n=36 Participants
Race (NIH/OMB) White	369 Participants n=5 Participants	372 Participants n=7 Participants	365 Participants n=5 Participants	360 Participants n=4 Participants	361 Participants n=21 Participants	362 Participants n=8 Participants	367 Participants n=8 Participants	358 Participants n=24 Participants	363 Participants n=42 Participants	369 Participants n=42 Participants	359 Participants n=42 Participants	353 Participants n=42 Participants	4358 Participants n=36 Participants
Race (NIH/OMB) More than one race	12 Participants n=5 Participants	13 Participants n=7 Participants	10 Participants n=5 Participants	11 Participants n=4 Participants	11 Participants n=21 Participants	12 Participants n=8 Participants	13 Participants n=8 Participants	14 Participants n=24 Participants	15 Participants n=42 Participants	9 Participants n=42 Participants	13 Participants n=42 Participants	14 Participants n=42 Participants	147 Participants n=36 Participants
Race (NIH/OMB) Unknown or Not Reported	26 Participants n=5 Participants	23 Participants n=7 Participants	37 Participants n=5 Participants	33 Participants n=4 Participants	32 Participants n=21 Participants	31 Participants n=8 Participants	27 Participants n=8 Participants	34 Participants n=24 Participants	32 Participants n=42 Participants	28 Participants n=42 Participants	26 Participants n=42 Participants	39 Participants n=42 Participants	368 Participants n=36 Participants

PRIMARY outcome

Timeframe: 7 days

The proportion of participants that answers all three survey questions via text message among all those randomized.

Outcome measures

Outcome measures
Measure	Arm 1 (Introductory Message A + Tobacco Use Message A + Incentive) n=509 Participants Participants will receive two framed messages (AA) plus an incentive Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 2 (Introductory Message A + Tobacco Use Message A) n=509 Participants Participants will receive two framed messages (AA) Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 3 (Introductory Message A + Tobacco Use Message B + Incentive) n=515 Participants Participants will receive two framed messages (AB) plus an incentive Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 4 (Introductory Message A + Tobacco Use Message B) n=509 Participants Participants will receive two framed messages (AB) Framed Introductory Message A: Randomly assign patients to receive introductory message encouraging them to complete the survey (version A). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Arm 5 (Introductory Message B + Tobacco Use Message A + Incentive) n=510 Participants Participants will receive two framed messages (BA) plus an incentive Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 6 (Introductory Message B + Tobacco Use Message A) n=510 Participants Participants will receive two framed messages (BA) Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 7 (Introductory Message B + Tobacco Use Message B + Incentive) n=512 Participants Participants will receive two framed messages (BB) plus an incentive Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 8 (Introductory Message B + Tobacco Use Message B) n=509 Participants Participants will receive two framed messages (BB) Framed Introductory Message B: Randomly assign patients to receive introductory message encouraging them to complete the survey (version B). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).	Arm 9 (Introductory Message C + Tobacco Use Message A + Incentive) n=511 Participants Participants will receive two framed messages (CA) plus an incentive Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 10 (Introductory Message C + Tobacco Use Message A) n=511 Participants Participants will receive two framed message (CA) Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message A: Randomly assign patients to receive norming message related to tobacco use (version A).	Arm 11 (Introductory Message C + Tobacco Use Message B + Incentive) n=509 Participants Participants will receive two framed messages (CB) plus an incentive Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B). Financial Incentive: Randomly assigned patients to be entered into a drawing to receive a $100 gift card.	Arm 12 (Introductory Message C + Tobacco Use Message B) n=511 Participants Participants will receive two framed messages (CB) Framed Introductory Message C: Randomly assign patients to receive introductory message encouraging them to complete the survey (version C). Framed Tobacco Use Message B: Randomly assign patients to receive norming message related to tobacco use (version B).
Full Survey Completion	358 Participants	381 Participants	383 Participants	389 Participants	372 Participants	399 Participants	386 Participants	402 Participants	335 Participants	397 Participants	373 Participants	366 Participants

SECONDARY outcome

Timeframe: 7 days

The proportion of participants that answer at least one of three survey questions via text message among all those randomized.