Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)
NCT ID: NCT06133244
Last Updated: 2024-05-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
300 participants
OBSERVATIONAL
2024-04-19
2028-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
OTHER
Study Groups
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VEDOSS
defined as RP, presence of SSc specific autoantibodies (ACA, ATA, ARA), puffy fingers and abnormal nailfold capillaroscopy (giant capillaries or capillary loss with or without haemorrhages), but not fulfilling the EULAR-ACR 2013 classification criteria for SSc
Imaging, blood samples, fuctional tests and physical examination
Imaging, blood samples, fuctional tests and physical examination
SSc with disease duration of < 4 years without hand contractures
Imaging, blood samples, fuctional tests and physical examination
Imaging, blood samples, fuctional tests and physical examination
SSc with hand contractures
Imaging, blood samples, fuctional tests and physical examination
Imaging, blood samples, fuctional tests and physical examination
Interventions
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Imaging, blood samples, fuctional tests and physical examination
Imaging, blood samples, fuctional tests and physical examination
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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University Medical Center Groningen
OTHER
Radboud University Medical Center
OTHER
Leiden University Medical Center
OTHER
Royal Free Hospital NHS Foundation Trust
OTHER
UMC Utrecht
OTHER
Responsible Party
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Julia Spierings, MD PhD
Dr.
Locations
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UMC Utrecht
Utrecht, , Netherlands
Countries
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Facility Contacts
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References
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Greveling M, Ong VH, Denton C, Foppen W, Herman A, Jeffries-Owen N, Kortekaas M, Masselink I, Mulder DJ, Schriemer R, Vonk MC, de Vries-Bouwstra JK, Welsing P, Mastbergen S, Spierings J. Hand function impairment in Systemic sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) - a longitudinal observational multicentre study protocol. BMJ Open. 2025 Mar 13;15(3):e095283. doi: 10.1136/bmjopen-2024-095283.
Other Identifiers
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NL85445.041.23
Identifier Type: -
Identifier Source: org_study_id
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