Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis

NCT ID: NCT02212249

Last Updated: 2016-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

85 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2016-03-31

Brief Summary

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Ve-cadherin is expressed in endothelial cells. Systemic slerosis is a rare auto-immune disease with a endothelial dysfunction. This study is to evaluated the level of soluble VE-cadherin and VE-cadherin antibody in patients with systemic slerosis.

Detailed Description

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Conditions

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Primary Raynaud Disease Systemic Sclerosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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Systemic sclerosis

patients with systemic sclerosis

Group Type ACTIVE_COMPARATOR

soluble Ve cadherin

Intervention Type BIOLOGICAL

dosage of soluble VE cadherine in each arms

primary raynaud disease

patients with primary raynaud disease

Group Type SHAM_COMPARATOR

soluble Ve cadherin

Intervention Type BIOLOGICAL

dosage of soluble VE cadherine in each arms

Interventions

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soluble Ve cadherin

dosage of soluble VE cadherine in each arms

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* group 1: systemic sclerosis
* group 2: raynaud primary disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Grenoble University Hospital

Grenoble, , France

Site Status

Countries

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France

Other Identifiers

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2014-A00186-41

Identifier Type: -

Identifier Source: org_study_id

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