Efficacy Evaluation of Two Different Fluoride Applications
NCT ID: NCT06131294
Last Updated: 2025-10-23
Study Results
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View full resultsBasic Information
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COMPLETED
NA
23 participants
INTERVENTIONAL
2023-02-24
2024-04-16
Brief Summary
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Each patient will receive both treatments in a split-mouth design. It is comparison between an experimental fluoride application and Fluoride Protector S.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Expermental Fluoride Application
The two-step system, consisting of Component A (ammonium fluoride solution) and Component B (calcium fluoride application), will be applied once on the white spot lesions one.
Fluoride Application (Experimental Fluoride Application)
Fluoride containing applications are applied on white spot lesions. First solution was air-dried before the second application with the other component was done.
Fluor Protector S
The ammonium fluoride gel will be applied once on the white spot lesions.
Fluor Protector S
Fluor Protector S is applied on white spot lesions.
Interventions
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Fluoride Application (Experimental Fluoride Application)
Fluoride containing applications are applied on white spot lesions. First solution was air-dried before the second application with the other component was done.
Fluor Protector S
Fluor Protector S is applied on white spot lesions.
Eligibility Criteria
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Inclusion Criteria
* Age between 13 and 50 years
* No untreated caries lesions or periodontal disease
* No systematic disease or medication (such as antidepressants, antibiotics etc.) that affects salivary flow rate
* Subjects claimed regular brushing at least twice a day
* Subjects had to agree to keep the scheduled recall appointments for at least 1 year.
Exclusion Criteria
* Lesions with microcavity, cavitation, chipping or discoloration
* Lesions at buccal side of the molars
* Lesions adjacent to restoration
* Developmental white spot lesions such as enamel hypoplasia
* Pregnancy
13 Years
50 Years
ALL
No
Sponsors
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Istanbul Medipol University Hospital
OTHER
Ivoclar Vivadent AG
INDUSTRY
Responsible Party
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Principal Investigators
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Burcu Gözetici, Dr.
Role: PRINCIPAL_INVESTIGATOR
Istanbul Medipo University
Locations
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Istanbul Medipo University
Istanbul, Esenler, Turkey (Türkiye)
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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LL4470462
Identifier Type: -
Identifier Source: org_study_id
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