A Research Study in Italy to Understand How the Dose Check App Used With Xultophy® Works in the Treatment of People Living With Type 2 Diabetes

NCT ID: NCT06113341

Last Updated: 2024-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-07

Study Completion Date

2026-03-02

Brief Summary

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This study will look at how a mobile based app called 'Dose Check' used along with Xultophy® helps the treatment in participants with type 2 diabetes mellitus (T2DM). Participants will get Xultophy® as prescribed by study doctor or will continue already prescribed treatment with Xultophy®. Participants will also be prescribed to use Dose Check app by study doctor. Participants will be asked to install the Dose Check app in their mobile phone, which will be supported with the correct dose of Xultophy®. The study will last for about 6 to 8 months.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 2

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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IDegLira + Dose Check

Participants will be treated with commercially available Xultophy® (IDegLira) used with Dose Check app according to local label and routine clinical practice at the discretion of the treating physician.

IDegLira

Intervention Type DRUG

Pre-filled pen injection.

Interventions

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IDegLira

Pre-filled pen injection.

Intervention Type DRUG

Other Intervention Names

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Xultophy

Eligibility Criteria

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Inclusion Criteria

* Signed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol).
* Male or female, age above or equal to 21 years at the time of signing informed consent.
* Diagnosed with T2DM \>=12 weeks prior to signing consent.
* The decision to initiate treatment with commercially available Dose Check app as a part of treatment along with Xultophy® as per the local label has been made by the patient and the treating physician before and independently from the decision to include the participant in this study.
* Participants who are insulin naive (including the following situations: i. already on treatment with Xultophy® at V1 for less than or equal to (\<=) 12 months and for \<= 15 dose steps and ii. short-term insulin use for acute illness for a total of \<14 days)
* Available HbA1c value \<=12 weeks prior to the 'Informed consent and initiation of Dose Check app visit' (V1) or HbA1c measurement taken in relation with the 'Informed consent and initiation of Dose Check app visit' (V1), if in line with local clinical practice.
* Willingness to continue using the Dose Check app on a compatible smartphone according to the intended use for the entire duration of the study.

Exclusion Criteria

* Previous participation in this study. Participation is defined as having signed informed consent in this study.
* Women known to be pregnant or breastfeeding, or women planning to become pregnant during the conduct of the study.
* Treatment with any investigational drug or software as a medical device (SaMD) within 30 days prior to enrolment into the study.
* Diagnosed with type 1 diabetes mellitus.
* Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation.
* Hypersensitivity to the active substance or any of the excipients as specified in the Xultophy® local label.
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Transparency (dept. 2834)

Role: STUDY_DIRECTOR

Novo Nordisk A/S

Locations

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Azienda Ospedaliero-Universitaria Renato Dulbecco

Catanzaro, Cz, Italy

Site Status

Azienda Ospedaliero Universitario Policlinico "G. Martino"

Gazi, ME, Italy

Site Status

Azienda Ospedaliera Cannizzaro

Catania, Sicily, Italy

Site Status

A.O. SS Antonio e Biagio e Cesare Arrigo

Alessandria, , Italy

Site Status

Azienda Ospedaliera Ospedale Policlinico Consorziale

Bari, , Italy

Site Status

Azienda Ospedaliero-Universitaria Renato Dulbecco

Catanzaro, , Italy

Site Status

Ospedale di Chivasso

Chivasso, , Italy

Site Status

Presidio Ospedale di Cittadella Azienda ULSS 6 Euganea

Cittadella, , Italy

Site Status

Ospedale Santa Croce

Fano, , Italy

Site Status

Presidio Ospedaliero Santa Barbara

Iglesias, , Italy

Site Status

IRCCS Ospedale Sacro Cuore Don Calabria

Negrar, , Italy

Site Status

Ospedale San Francesco d'Assisi

Oliveto Citra, , Italy

Site Status

ARNAS Ospedali Civico Di Cristina Benfratelli

Palermo, , Italy

Site Status

Azienda Ospedaliero Universitaria Pisana Ospedale Cisanello

Pisa, , Italy

Site Status

Nuovo Ospedale degli Infermi

Ponderano, , Italy

Site Status

DIABETOLOGIA Ravenna AUSL della Romagna

Ravenna, , Italy

Site Status

AUSL Reggio Emilia

Reggio Emilia, , Italy

Site Status

A.O.U. Policlinico Umberto I

Roma, , Italy

Site Status

Fondazione Univ. Policlinico A.Gemelli

Roma, , Italy

Site Status

Countries

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Italy

Other Identifiers

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U1111-1288-8131

Identifier Type: OTHER

Identifier Source: secondary_id

NN9068-7589

Identifier Type: -

Identifier Source: org_study_id

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