Use of Incretins in Diabetic Patients

NCT ID: NCT03486964

Last Updated: 2022-05-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2234 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-27

Study Completion Date

2021-05-30

Brief Summary

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Observational, retrospective study, conducted in diabetic patients aimed to evaluate the effects on the glyco-metabolic control and on cardiovascular events of different DPP-4 inhibitors. Patients will be stratified in patients taking different DPP-4 in addition to sulfonylureas, biguanides, thiazolidinediones, insulin, compared to those in therapy with other hypoglycemic classes, such as sulphonylureas, biguanides, thiazolidinediones, insulin, alone or in combination, in primary and secondary prevention.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 2

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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DPP-4 plus other therapies

Patients in therapy with DPP-4 inhibitors in addition to sulfonylureas and/or biguanides and/or thiazolidinediones and/or insulin

DPP-4 inhibitors

Intervention Type DRUG

Patients will be retrospectively evaluated after the addition of a DPP-4 inhibitor to previously taken anti-diabetic therapy

Other therapies

Patients in therapy with other hypoglycemic classes, such as sulphonylureas and/or biguanides and/or thiazolidinediones and/or insulin.

No interventions assigned to this group

Interventions

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DPP-4 inhibitors

Patients will be retrospectively evaluated after the addition of a DPP-4 inhibitor to previously taken anti-diabetic therapy

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Type 2 diabetic patients
* On oral hypoglycemic agents ± basal insulin
* In primary and secondary prevention

Exclusion Criteria

\- Patients with a follow-up of less than 8 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Pavia

OTHER

Sponsor Role lead

Responsible Party

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Giuseppe Derosa

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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IRCCS Policlinico San Matteo Foundation

Pavia, Lombardy, Italy

Site Status

Countries

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Italy

Other Identifiers

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P-20180016468

Identifier Type: -

Identifier Source: org_study_id

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