Role of Membrane Sweeping on Initiation of Labor and Vaginal Birth in Previous Cesarean Section

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

384 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-15

Study Completion Date

2024-08-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In Pakistan rate of child birth through cesarean section increased from 3.2% in 1992 to 22% in 2018 .Due to increasing rates of cesarean sections and associated morbidity the investigators should focus to reduce rate of primary cesarean section as well as repeat cesarean with cephalic presentation and singleton pregnancy after previous 1 cesarean section. Therefore, all ladies who underwent previous 1 cesarean section for non-recurrent cause should be considered for vaginal birth. Though studies show that membrane sweeping does promote the onset of labor and avoid need for formal induction of labor for prolonged pregnancy but the effects of membrane sweeping in women with a prior cesarean delivery are largely unknown. This is a randomized controlled trial. Objective of the study was to determine the effect of membrane sweeping on the onset of labor, success of vaginal delivery and neonatal outcome in patients with previous one cesarean section.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Membrane Sweeping Versus Transcervical Foley Catheter for Induction of Labour in Women With Previous Caesarean Delivery

NCT03326557

Labour, Induced Vaginal Birth After Caesarean

COMPLETED NA

Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function

NCT00517140

Pregnancy Cesarean Section Uterine Rupture

COMPLETED NA

EFFECTIVENESS OF PREOPERATIVE VAGINAL CLEANING IN REDUCING POST CAESAREAN INFECTIOUS MORBIDITY

NCT07053995

Endometrial Infection Surgical Site Infection Following Cesarean Delivery

COMPLETED NA

Comparison of the Frequency of Post-Operative Pain of Continuous Versus Interrupted Suturing Techniques in Episiotomy

NCT07050615

Post Operative Pain

COMPLETED NA

How Well do the Current Cesarean Deliveries Adhere to the Published ERAS Guidelines?

NCT05396417

Cesarean Section Complications

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

World Health Organization suggests that ideally cesarean section rate should not be more than 10% to 15%. The investigators should focus to reduce rate of primary cesarean section as well as repeat cesarean with cephalic presentation and singleton pregnancy after previous 1 cesarean section. Therefore, all ladies who underwent previous 1 cesarean section for non-recurrent cause should be considered for vaginal birth. Though studies show that membrane sweeping does promote the onset of labor and avoid need for formal induction of labor for prolonged pregnancy but the effects of membrane sweeping in women with a prior cesarean delivery are largely unknown. It is reported in literature that there is no significant increase risk to maternal or neonatal outcome with membrane sweeping. The rationale of the study was to compare the effect of membrane sweeping with no sweeping in the successful onset of labor in patients with one previous Cesarean Section so that the investigators can reduce the cesarean section rate. Objective of the study was to determine the effect of membrane sweeping on the onset of labor, success of vaginal delivery and neonatal outcome in patients with previous one cesarean section.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Vaginal Birth After Cesarean Section

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

randomization intervention RCT

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

lottery method for selection

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Sweeping group

Sweeping group include patients in which membrane sweeping started from 37 weeks and performed weekly till 40 weeks. Intervention is the sweeping of membranes from 37 weeks of gestational amenorrhea.

Group Type ACTIVE_COMPARATOR

Sweeping of membranes

Intervention Type PROCEDURE

After informed consent all the patients in interventional group will have sweeping of membranes from 37 weeks of pregnancy . It will be repeated weekly till 40 weeks.

Non sweeping group

Non sweeping group include patients in which no sweeping of membranes done. No intervention done.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Sweeping of membranes

After informed consent all the patients in interventional group will have sweeping of membranes from 37 weeks of pregnancy . It will be repeated weekly till 40 weeks.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 1\. Women willing for vaginal birth after lower segment cesarean section from 37 weeks of gestation to 40 weeks.

2\. Previous one caesarean section for non-recurrent cause 3. Singleton pregnancy 4. Cephalic presentation